MAT2B: Potential Drug Target Or Biomarker (G27430)

Target Name: MAT2B

NCBI ID: G27430

MAT2B: Potential Drug Target Or Biomarker

MAT2B, or Methionine adenosyltransferase 2 subunit beta (isoform 2), is a protein that is expressed in various tissues throughout the body. It plays a crucial role in the regulation of methionine, a crucial amino acid that is involved in the structure and function of many proteins. MAT2B is also involved in the transfer of adenosyl groups, which are crucial for the proper functioning of proteins.

Recent studies have suggested that MAT2B may be a potential drug target or biomarker for a variety of diseases. This is because MAT2B is involved in the regulation of many important cellular processes, and alterations in its expression or function have been observed in a wide range of diseases.

One of the potential benefits of targeting MAT2B is its involvement in the regulation of protein synthesis. MAT2B is known to play a role in the transfer of adenosyl groups, which are crucial for the initiation of protein synthesis. This means that MAT2B may be a useful target for drugs that are designed to inhibit protein synthesis.

Another potential benefit of targeting MAT2B is its involvement in the regulation of cellular stress responses. MAT2B has been shown to play a role in the regulation of cellular stress responses, and alterations in its expression have been observed in a variety of diseases that are characterized by cellular stress. This suggests that MAT2B may be a useful target for drugs that are designed to promote cellular stress responses or inhibit stress responses.

In addition to its potential role in drug targeting, MAT2B has also been shown to be a potential biomarker for a variety of diseases. For example, MAT2B has been shown to be expressed in a variety of tissues and has been used as a biomarker for a variety of diseases, including cancer, neurodegenerative diseases, and autoimmune diseases.

Overall, MAT2B is a protein that is involved in a wide range of cellular processes and has been implicated in the regulation of many important cellular processes. As such, it is a potential drug target or biomarker for a variety of diseases. Further research is needed to fully understand the role of MAT2B in cellular processes and its potential as a drug target or biomarker.

Protein Name: Methionine Adenosyltransferase 2B

Functions: Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine (PubMed:10644686, PubMed:23189196, PubMed:25075345). Can bind NADP (in vitro) (PubMed:23189196, PubMed:23425511)

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