MAST1: A Non-Coding RNA Molecule Regulating Cellular Processes
MAST1: A Non-Coding RNA Molecule Regulating Cellular Processes
MAST1 (MutL1-Activating Sequence-1) is a non-coding RNA molecule that plays a critical role in the regulation of gene expression in various organisms, including humans. It is a key regulator of cell proliferation and has been implicated in the development and progression of various diseases, including cancer.
The MAST1 gene is located on chromosome 18 and contains 21 exons. It is expressed in various tissues and cells throughout the body, including the brain, heart, and gastrointestinal tract. It is a key regulator of cell proliferation and has been implicated in the development and progression of various diseases, including cancer.
One of the unique features of MAST1 is its ability to induce cell proliferation both in healthy cells and in cancer cells. This is accomplished through the regulation of key signaling pathways, including the TGF-β pathway. TGF-β is a cytokine that plays a critical role in the regulation of cell growth, differentiation, and survival. The TGF-β pathway is composed of multiple transcription factors, including MAST1, that work together to regulate gene expression and induce cell proliferation.
MAST1 has also been shown to play a key role in the regulation of cell apoptosis, which is the process by which cells die and are removed from the body. This is accomplished through the regulation of key signaling pathways, including the p53 pathway. The p53 pathway is a critical regulator of gene expression and has been shown to play a key role in the regulation of cell apoptosis.
In addition to its role in cell proliferation and apoptosis, MAST1 has also been shown to play a critical role in the regulation of cell adhesion. This is accomplished through the regulation of key signaling pathways, including the cadherin pathway. The cadherin pathway is a critical regulator of cell adhesion and has been shown to play a key role in the regulation of various physiological processes, including cell migration and the development of cancer.
MAST1 has also been shown to play a critical role in the regulation of cellular processes that are important for overall health and well-being. This is accomplished through the regulation of key signaling pathways, including the Wnt pathway. The Wnt pathway is a critical regulator of cell growth and development and has been shown to play a key role in the regulation of various physiological processes, including fetal development and the development of cancer.
In conclusion, MAST1 is a non-coding RNA molecule that plays a critical role in the regulation of gene expression in various organisms, including humans. It is a key regulator of cell proliferation, apoptosis, and adhesion and has been implicated in the development and progression of various diseases, including cancer. Further research is needed to fully understand the role of MAST1 in the regulation of cellular processes and to develop effective treatments for various diseases.
Protein Name: Microtubule Associated Serine/threonine Kinase 1
Functions: Microtubule-associated protein essential for correct brain development (PubMed:30449657). Appears to link the dystrophin/utrophin network with microtubule filaments via the syntrophins. Phosphorylation of DMD or UTRN may modulate their affinities for associated proteins (By similarity)
More Common Targets
MAST2 | MAST3 | MAST4 | MASTL | MAT1A | MAT2A | MAT2B | MATCAP1 | MATCAP2 | MATK | MATN1 | MATN1-AS1 | MATN2 | MATN3 | MATN4 | MATR3 | Matrix Metalloproteinase (MMP) | MAU2 | MAVS | MAX | MAZ | MB | MB21D2 | MBD1 | MBD2 | MBD2-MBD3 complex | MBD3 | MBD3L1 | MBD3L2 | MBD3L3 | MBD3L4 | MBD3L5 | MBD4 | MBD5 | MBD6 | MBIP | MBL1P | MBL2 | MBLAC1 | MBLAC2 | MBNL1 | MBNL1-AS1 | MBNL2 | MBNL3 | MBOAT1 | MBOAT2 | MBOAT4 | MBOAT7 | MBP | MBTD1 | MBTPS1 | MBTPS2 | MC1R | MC2R | MC3R | MC4R | MC5R | MCAM | MCAT | MCC | MCCC1 | MCCC2 | MCCD1 | MCCD1P1 | MCEE | MCEMP1 | MCF2 | MCF2L | MCF2L-AS1 | MCF2L2 | MCFD2 | MCFD2P1 | MCHR1 | MCHR2 | MCHR2-AS1 | MCIDAS | MCL1 | MCM10 | MCM2 | MCM3 | MCM3AP | MCM3AP-AS1 | MCM4 | MCM5 | MCM6 | MCM7 | MCM8 | MCM8-MCM9 complex | MCM9 | MCMBP | MCMDC2 | MCOLN1 | MCOLN2 | MCOLN3 | MCPH1 | MCPH1-AS1 | MCPH1-DT | MCRIP1 | MCRIP2 | MCRS1