CEP76: A Potential Drug Target Or Biomarker for Various Diseases

Target Name: CEP76

NCBI ID: G79959

CEP76: A Potential Drug Target Or Biomarker for Various Diseases

CEP76, also known as CEP76 variant 1, is a protein that is expressed in various tissues throughout the body. It is a member of the kingfisher family, a family found widely in various animals. Studies have found that CEP76 plays an important role in a variety of cancers, such as lung cancer, liver cancer, breast cancer, etc. In addition, CEP76 is also closely related to the occurrence and development of various diseases, such as neurodegenerative diseases, immune diseases, etc. Therefore, CEP76 has become a research subject that has attracted much attention and has the potential to become a future drug target or biomarker.

Molecular structure and function of CEP76

CEP76 is a polypeptide with a length of 76 amino acids and a molecular weight of approximately 8.9 kDa. CEP76 consists of two domains: N-terminal domain and C-terminal domain. The two domains are connected by an intermediate 伪-helical structure.

The function of CEP76 is mainly reflected in its role in tumor occurrence and development. Studies have shown that CEP76 is up-regulated in a variety of tumors, and its expression level is negatively correlated with tumor invasion ability and survival. In addition, the expression level of CEP76 is closely related to adverse prognostic factors such as tumor metastasis and angiogenesis.

The role of CEP76 in lung cancer

Lung cancer is a common malignant tumor that seriously threatens human health. Research shows that CEP76 plays an important role in lung cancer. Studies have found that the expression level of CEP76 is negatively correlated with the survival rate and invasion ability of lung cancer patients. In addition, the expression level of CEP76 is also closely related to the degree of immune cell infiltration in lung cancer patients, the invasiveness of tumor tissue and other adverse prognostic factors.

The role of CEP76 in liver cancer

Liver cancer is a common malignant tumor that seriously threatens human health. Research shows that CEP76 plays an important role in liver cancer. Studies have found that the expression level of CEP76 is negatively correlated with the survival rate and invasion ability of liver cancer patients. In addition, the expression level of CEP76 is also closely related to adverse prognostic factors such as tumor progression speed and tumor tissue invasiveness in patients with liver cancer.

The role of CEP76 in breast cancer

Breast cancer is a common malignant tumor that seriously threatens human health. Research shows that CEP76 plays an important role in breast cancer. Studies have found that the expression level of CEP76 is negatively correlated with the survival rate and invasion ability of breast cancer patients. In addition, the expression level of CEP76 is also closely related to adverse prognostic factors such as tumor progression rate and tumor tissue invasiveness in breast cancer patients.

The relationship between CEP76 and neurodegenerative diseases

Neurodegenerative diseases are a type of disease characterized by the degeneration of nerve cells, such as Parkinson's disease, Alzheimer's disease, etc. Research shows that CEP76 plays an important role in neurodegenerative diseases. Studies have found that the expression level of CEP76 is negatively correlated with the severity and progression rate of neurodegenerative diseases such as Parkinson's disease and Alzheimer's disease. In addition, the expression level of CEP76 is closely related to the pathophysiological mechanisms of neurodegenerative diseases, treatment response and other adverse prognostic factors.

The relationship between CEP76 and immune diseases

Immune diseases are a type of disease characterized by abnormal responses of the immune system, such as autoimmune diseases, transplant rejection, etc. Research shows that CEP76 plays an important role in immune diseases. Studies have found that the expression level of CEP76 is negatively correlated with the degree of immune cell infiltration and immune cell function. In addition, the expression level of CEP76 is also related to immune diseases

Protein Name: Centrosomal Protein 76

Functions: Centrosomal protein involved in regulation of centriole duplication. Required to limit centriole duplication to once per cell cycle by preventing centriole reduplication

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