CFAP43: Potential Drug Target Or Biomarker (G80217)

Target Name: CFAP43

NCBI ID: G80217

CFAP43: Potential Drug Target Or Biomarker

CFAP43 (Cilia and flagella associated protein 43) is a protein that is expressed in the ciliated epithelial cells of the human body. It is a member of the flagellin family and is involved in the regulation of cilia function. CFAP43 has been shown to play a role in the development and maintenance of ciliature in the human airway, which is a critical aspect of airway health.

Recent studies have suggested that CFAP43 may have potential as a drug target or biomarker. One reason for this is that CFAP43 has been shown to be involved in the regulation of several important cellular processes, including cell signaling, cell migration, and cell adhesion. Additionally, studies have shown that CFAP43 is expressed in various tissues and organs, including the lungs, heart, brain, and pancreas, which suggests that it may be a useful biomarker for tracking disease progression.

Another reason for the potential utility of CFAP43 as a drug target is its role in the development of respiratory diseases, such as chronic obstructive pulmonary disease (COPD) and asthma. Studies have shown that CFAP43 is expressed in the airways of individuals with these conditions and that it is involved in the regulation of ciliature, which is a critical factor in the development of these diseases. Additionally, some studies have suggested that inhibiting CFAP43 may be a potential approach to treating respiratory diseases by reducing ciliation and improving airway health.

CFAP43 has also been shown to be involved in the regulation of other important cellular processes, including cell signaling, cell migration, and cell adhesion. Studies have shown that CFAP43 plays a role in the regulation of T cell development and function, which is important for the immune response. Additionally, CFAP43 has been shown to be involved in the regulation of mitochondrial function, which is important for energy metabolism and cell survival.

In conclusion, CFAP43 is a protein that is expressed in the ciliated epithelial cells of the human body and is involved in the regulation of ciliature. It has been shown to play a role in the development and maintenance of ciliature in the human airway, as well as several other important cellular processes. As a result, CFAP43 may have potential as a drug target or biomarker for the treatment of respiratory diseases. Further research is needed to fully understand its role and potential utility as a drug.

Protein Name: Cilia And Flagella Associated Protein 43

Functions: Flagellar protein involved in sperm flagellum axoneme organization and function (By similarity). Involved in the regulation of the beating frequency of motile cilia on the epithelial cells of the respiratory tract (By similarity)

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