CEP70: A Protein Role in Cell Division and Beyond (G80321)

Target Name: CEP70

NCBI ID: G80321

CEP70: A Protein Role in Cell Division and Beyond

Centrosomal protein 70 (CEP70) is a protein that is expressed in various cell types, including neurons, neural transition cells and embryonic stem cells. CEP70 plays a crucial role in the proper functioning of the cell, particularly during the cell division process. It is a key component of the centrosome, which is the structure that forms the centrioles and participates in the mitotic process.

CEP70 is a transmembrane protein that is expressed in the cytoplasm and the endoplasmic reticulum. It consists of 150 amino acids and has a calculated molecular weight of 19.9 kDa. CEP70 is highly conserved, with only one known splice variant.

During cell division, CEP70 plays a vital role in the formation and stability of the centrosome. It helps to maintain the stability of the centrosome by interacting with the microtubules of the mitotic spindle. CEP70 is also involved in the regulation of cell cycle progression, and it has been shown to play a role in the transition from G1 to G2 phase of the cell cycle.

In addition to its role in cell division, CEP70 has also been shown to play a role in various other cellular processes. For example, it has been shown to be involved in the regulation of cell adhesion, and it has been shown to play a role in the development and maintenance of neural stem cells.

As a drug target, CEP70 is a promising target for the development of new treatments for various diseases. For example, studies have shown that inhibiting CEP70 can lead to the inhibition of the growth of cancer cells, and it has been shown to be effective in treating various diseases, including cancer.

In addition to its potential as a drug target, CEP70 is also a potential biomarker for certain diseases. For example, studies have shown that the expression of CEP70 is decreased in various types of cancer, and it has been shown to be a potential biomarker for cancer.

Overall, CEP70 is a protein that plays a crucial role in the functioning of the cell. It is a potential drug target and biomarker, and further research is needed to fully understand its role in various cellular processes.

Protein Name: Centrosomal Protein 70

Functions: Plays a role in the organization of both preexisting and nascent microtubules in interphase cells. During mitosis, required for the organization and orientation of the mitotic spindle

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