Target Name: MIGA2
NCBI ID: G84895
Other Name(s): mitoguardin 2 | Mitoguardin 2 (isoform 1) | Mitoguardin 2, transcript variant 1 | C9orf54 | FAM73B | MIGA2 variant 1 | protein FAM73B | family with sequence similarity 73, member B | MIGA2_HUMAN | Mitoguardin 2

MIGA2: A Potential Drug Target and Biomarker

Mitoguardin 2 (MIGA2) is a protein that is expressed in various tissues of the body, including the brain, heart, liver, and kidneys. It is a member of the Mitoguardin family, which includes several similar proteins that play a critical role in cellular signaling pathways. One of the unique features of MIGA2 is its potential as a drug target and biomarker.

The Mitoguardin family of proteins are characterized by the presence of a nucleotide-binding oligomerization domain (NBD), which is a common structural motif that is involved in protein-protein interactions. MIGA2 is no exception, and it has a NBD that is involved in several cellular signaling pathways.

One of the key functions of MIGA2 is its role in the regulation of cell proliferation. MIGA2 has been shown to play a critical role in the regulation of cell proliferation both in normal development and in the treatment of cancer. MIGA2 has been shown to inhibit the growth of cancer cells in cell culture and in animal models of cancer.

In addition to its role in cell proliferation, MIGA2 has also been shown to play a critical role in the regulation of cell apoptosis (programmed cell death). MIGA2 has been shown to promote the apoptosis of cancer cells, which may contribute to the anti- cancer effects of MIGA2.

MIGA2 has also been shown to play a critical role in the regulation of cellular signaling pathways that are involved in inflammation and immune responses. MIGA2 has also been shown to be involved in the regulation of T cell responses to antigens, which may contribute to its potential as a vaccine or cancer immunotherapy.

MIGA2 has also been shown to play a critical role in the regulation of cellular signaling pathways that are involved in neurodegenerative diseases. MIGA2 has also been shown to be involved in the regulation of neurotransmitter release from neurons, which may contribute to the development of neurodegenerative diseases..

In conclusion, MIGA2 is a protein that has been shown to play a critical role in several cellular signaling pathways that are involved in cell proliferation, apoptosis, inflammation, and immune responses. Its potential as a drug target and biomarker makes it an attractive target for further research. Further studies are needed to fully understand the role of MIGA2 in cellular signaling pathways and its potential as a drug target and biomarker.

Protein Name: Mitoguardin 2

Functions: Regulator of mitochondrial fusion: acts by forming homo- and heterodimers at the mitochondrial outer membrane and facilitating the formation of PLD6/MitoPLD dimers. May act by regulating phospholipid metabolism via PLD6/MitoPLD

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