ACBD5: Key Protein Involved in Acyl-CoA Transport and Signaling
ACBD5: Key Protein Involved in Acyl-CoA Transport and Signaling
ACBD5, also known as Acyl-CoA binding domain containing 5, is a protein that is expressed in various tissues throughout the body. It is a key protein that is involved in the transport and metabolism of acyl-co acids, which are essential molecules in the body. ACBD5 is a transcript variant of the gene that encodes the protein.
The ACBD5 protein is composed of 158 amino acid residues and has a calculated molecular weight of 19.1 kDa. It is localized to the endoplasmic reticulum (ER) and is predominantly expressed in the liver, heart, and kidneys. It is also expressed in other tissues, including the brain, where it is thought to play a role in the regulation of neurotransmitter synthesis and release.
ACBD5 is involved in the transport and metabolism of acyl-co acids, which are essential molecules that are produced by the body and are used for a variety of cellular processes. Acyl-co acids are commonly found in various tissues and are involved in the production of hormones, neurotransmitters, and other signaling molecules. They are also involved in the regulation of cellular signaling pathways and are thought to play a key role in the development and progression of various diseases.
One of the unique features of ACBD5 is its ability to transport acyl-co acids across the endoplasmic reticulum (ER). The ER is a protein structure that is responsible for the final sorting of proteins into different cellular compartments. It is known that ACBD5 is able to interact with the protein transmembrane protein (TMP), which is also known as ABC transporter. This interaction allows ACBD5 to transport acyl-co acids across the ER and to the cytoplasm.
In addition to its role in acyl-co acid transport, ACBD5 is also involved in the regulation of cellular signaling pathways. It is a component of several signaling pathways that are involved in the regulation of cellular signaling pathways, including the TGF-β pathway and the Wnt signaling pathway.
ACBD5 is also involved in the regulation of cellular signaling pathways that are involved in the development and progression of various diseases. For example, studies have shown that ACBD5 is involved in the regulation of the development and progression of cancer. It has been shown to play a key role in the regulation of cell proliferation and to contribute to the development of cancer cell tumors.
In conclusion, ACBD5 is a protein that is involved in the transport and metabolism of acyl-co acids and is also involved in the regulation of cellular signaling pathways. Its unique ability to transport acyl-co acids across the endoplasmic reticulum makes it a potential drug target and a biomarker for various diseases. Further research is needed to fully understand the role of ACBD5 in the regulation of cellular signaling pathways and its potential as a drug target.
Protein Name: Acyl-CoA Binding Domain Containing 5
Functions: Acyl-CoA binding protein which acts as the peroxisome receptor for pexophagy but is dispensable for aggrephagy and nonselective autophagy. Binds medium- and long-chain acyl-CoA esters
More Common Targets
ACBD6 | ACBD7 | ACCS | ACCSL | ACD | ACE | ACE2 | ACE2-DT | ACE3P | ACER1 | ACER2 | ACER3 | Acetyl-CoA Carboxylases (ACC) | Acetylcholine Receptors (Nicotinic) (nAChR) | ACHE | Acid-Sensing Ion Channel (ASIC) | ACIN1 | ACKR1 | ACKR2 | ACKR3 | ACKR4 | ACKR4P1 | ACLY | ACMSD | ACO1 | ACO2 | ACOD1 | ACOT1 | ACOT11 | ACOT12 | ACOT13 | ACOT2 | ACOT4 | ACOT6 | ACOT7 | ACOT8 | ACOT9 | ACOX1 | ACOX2 | ACOX3 | ACOXL | ACOXL-AS1 | ACP1 | ACP2 | ACP3 | ACP4 | ACP5 | ACP6 | ACP7 | ACR | ACRBP | ACRV1 | ACSBG1 | ACSBG2 | ACSF2 | ACSF3 | ACSL1 | ACSL3 | ACSL4 | ACSL5 | ACSL6 | ACSM1 | ACSM2A | ACSM2B | ACSM3 | ACSM4 | ACSM5 | ACSM6 | ACSS1 | ACSS2 | ACSS3 | ACTA1 | ACTA2 | ACTA2-AS1 | ACTB | ACTBL2 | ACTBP12 | ACTBP2 | ACTBP3 | ACTBP8 | ACTBP9 | ACTC1 | ACTE1P | ACTG1 | ACTG1P1 | ACTG1P10 | ACTG1P12 | ACTG1P17 | ACTG1P20 | ACTG1P22 | ACTG1P25 | ACTG1P4 | ACTG2 | Actin | Activating signal cointegrator 1 complex protein | Activin receptor type 2 (nonspecifed subtype) | ACTL10 | ACTL6A | ACTL6B | ACTL7A