Target Name: NUP155
NCBI ID: G9631
Other Name(s): Nucleoporin Nup155 | NUP155 variant 1 | Nucleoporin 155kDa | ATFB15 | nucleoporin 155 | Nuclear pore complex protein Nup155 | nucleoporin 155kDa | Nucleoporin 155, transcript variant 1 | 155 kDa nucleoporin | N155 | NUP155 variant 2 | Nucleoporin 155, transcript variant 2 | Nuclear pore complex protein Nup155 (isoform 2) | NU155_HUMAN | KIAA0791 | nucleoporin 155kD | Nuclear pore complex protein Nup155 (isoform 1) | Nucleoporin 155kD

NUP155: A Promising Drug Target and Biomarker

Nucleoporin Nup155 (NUP155) is a drug target and a biomarker that is being studied for its potential utility in treating various diseases, including cancer. NUP155 is a small protein that is found in various cell types in the body, including neurons, muscle cells, and blood vessels. It is a nucleoporin, which means it has a role in regulating the movement of nuclear proteins into the cell.

One of the things that makes NUP155 an interesting drug target is its unique structure. NUP155 is made up of 155 amino acids and has a calculated molecular weight of 19.9 kDa. It is found in various tissues throughout the body and has been shown to play a role in various physiological processes, including cell signaling and protein transport.

One of the ways that NUP155 is being studied as a drug target is for its potential to treat cancer. NUP155 has been shown to promote the growth and survival of various cancer cell types, including breast, ovarian, and colorectal cancer cells. This makes it an attractive target for cancer treatments that aim to inhibit cell proliferation or kill cancer cells.

Another area where NUP155 is being studied is its potential as a biomarker. NUP155 has been shown to be expressed in various types of cancer, as well as in normal tissues and cells. This makes it a potential marker for cancer diagnosis and monitoring. Additionally, since NUP155 is found in a wide range of cell types, it could also be used as a marker for tracking the effectiveness of cancer treatments.

In addition to its potential as a cancer drug target and biomarker, NUP155 is also being studied for its effects on other cellular processes. For example, some researchers have shown that NUP155 can inhibit the migration of cells, which could be useful in treating diseases where cells are able to move and migrate to new areas. Additionally, NUP155 has been shown to interact with various signaling pathways, including the TGF-β pathway, which is involved in cell growth and development.

Overall, NUP155 is an interesting drug target and biomarker that is being studied for its potential utility in treating various diseases. Its unique structure and various cellular processes make it an attractive target for researchers to study, and its potential as a cancer drug and biomarker could make it an important addition to the arsenal of treatments for a variety of diseases.

Protein Name: Nucleoporin 155

Functions: Essential component of nuclear pore complex. Could be essessential for embryogenesis. Nucleoporins may be involved both in binding and translocating proteins during nucleocytoplasmic transport

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