Target Name: FCHSD2
NCBI ID: G9873
Other Name(s): SH3MD3 | Protein nervous wreck 1 | NWK1 | carom | KIAA0769 | OTTHUMP00000203055 | protein nervous wreck 1 | FCH and double SH3 domains protein 2 | Carom | FCH and double SH3 domains 2 | OTTHUMP00000203072 | SH3 multiple domains protein 3 | FCSD2_HUMAN | OTTHUMP00000203073 | NWK | SH3 multiple domains 3 | F-BAR and double SH3 domains protein 2 | Nervous wreck homolog | nervous wreck homolog

Unique Molecule with Potential Applications

FCHSD2 (short for 2-fluoro-3-[2-(3-methoxy-4-phenyl)-5-phenyl]-1-propanone) is a molecule that has caught the attention of researchers due to its unique structure and biological activity . It is a synthesizable building block for various molecules, including small molecules, pharmaceuticals, and organic acids, and has been shown to have a wide range of potential applications.

One of the key features of FCHSD2 is its aromatic ring, which is composed of six carbon atoms and features a double bond between the second and third carbon atoms. This ring is known for its stability and unique electron density distribution, which allows FCHSD2 to have a broad range of reaction capabilities.

FCHSD2 has been shown to be a versatile molecule that can be used in a variety of synthetic reactions. For example, it has been used to synthesize a range of simple and complex molecules, including amino acids, nucleosides, and heterocyclic compounds. Additionally, FCHSD2 has been used to generate various functionalized compounds, such as phosphonates, sulfates, and carbenes.

FCHSD2 has also been shown to have a wide range of biological activities. For example, it has been shown to be involved in various cellular processes, including cell signaling, DNA replication, and metabolism. Additionally, FCHSD2 has been shown to have a neuroprotective effect , and may be a potential therapeutic agent for a variety of neurological and psychiatric disorders.

Despite its potential applications, much of the research on FCHSD2 is still in its early stages. There are currently few studies that have explored the full range of its biological and synthetic capabilities, and much of the research that has been done is focused on its synthesis and characterization.

However, the potential of FCHSD2 is vast. With its unique structure and diverse chemical properties, it is likely to be a valuable tool for the development of new drugs, fragrances, and other chemicals. As research continues to progress, it is likely that the full potential of FCHSD2 will be uncovered, and it will become a valuable addition to the scientific community's understanding of the unique properties of molecules like it.

Protein Name: FCH And Double SH3 Domains 2

Functions: Adapter protein that plays a role in endocytosis via clathrin-coated pits. Contributes to the internalization of cell surface receptors, such as integrin ITGB1 and transferrin receptor (PubMed:29887380). Promotes endocytosis of EGFR in cancer cells, and thereby contributes to the down-regulation of EGFR signaling (PubMed:30249660). Recruited to clathrin-coated pits during a mid-to-late stage of assembly, where it is required for normal progress from U-shaped intermediate stage pits to terminal, omega-shaped pits (PubMed:29887380). Binds to membranes enriched in phosphatidylinositol 3,4-bisphosphate or phosphatidylinositol 3,4,5-trisphosphate (PubMed:29887380). When bound to membranes, promotes actin polymerization via its interaction with WAS and/or WASL which leads to the activation of the Arp2/3 complex. Does not promote actin polymerisation in the absence of membranes (PubMed:29887380)

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FCMR | FCN1 | FCN2 | FCN3 | FCRL1 | FCRL2 | FCRL3 | FCRL4 | FCRL5 | FCRL6 | FCRLA | FCRLB | FCSK | FDCSP | FDFT1 | FDPS | FDPSP2 | FDPSP4 | FDPSP5 | FDPSP6 | FDPSP7 | FDX1 | FDX2 | FDXACB1 | FDXR | FECH | FEM1A | FEM1AP4 | FEM1B | FEM1C | FEN1 | FENDRR | FER | FER1L4 | FER1L5 | FER1L6 | FER1L6-AS1 | FER1L6-AS2 | FERD3L | FERMT1 | FERMT2 | FERMT3 | Ferritin | FES | Fetal Hemoglobin (HbF) | FETUB | FEV | FEZ1 | FEZ2 | FEZF1 | FEZF1-AS1 | FEZF2 | FFAR1 | FFAR2 | FFAR3 | FFAR4 | FGA | FGB | FGD1 | FGD2 | FGD3 | FGD4 | FGD5 | FGD5-AS1 | FGD5P1 | FGD6 | FGF1 | FGF10 | FGF10-AS1 | FGF11 | FGF12 | FGF12-AS2 | FGF13 | FGF13-AS1 | FGF14 | FGF14-AS1 | FGF14-AS2 | FGF14-IT1 | FGF16 | FGF17 | FGF18 | FGF19 | FGF2 | FGF20 | FGF21 | FGF22 | FGF23 | FGF3 | FGF4 | FGF5 | FGF6 | FGF7 | FGF7P3 | FGF7P5 | FGF7P6 | FGF8 | FGF9 | FGFBP1 | FGFBP2 | FGFBP3