Target Name: FERMT1
NCBI ID: G55612
Other Name(s): UNC112 related protein 1 | Kindlerin | Kindlin-1 | UNC112A | Fermitin family homolog 1 | kindlin syndrome protein | DTGCU2 | KDN1 | Unc-112-related protein 1 | Kindlin 1 | unc-112-related protein 1 | FLJ23423 | URP1 | Chromosome 20 open reading frame 42 | KIND1 | fermitin family member 1 | kindlerin | FERM1_HUMAN | OTTHUMP00000030222 | UNC-112 related protein 1 | FLJ20116 | FERM domain containing kindlin 1 | C20orf42 | Kindlin syndrome protein | kindlin 1

FERMT1: A Protein Involved in Myosin Activity and Cellular Processes

FERMT1 (UNC112-related protein 1) is a protein that is expressed in various tissues of the body, including muscle, heart, and brain. It is a member of the family of proteins known as myosin-related proteins, which are involved in the regulation of muscle contractions.

FERMT1 is unique because of its ability to interact with and regulate the activity of other proteins, particularly the myosin protein. Myosin is a protein that is involved in the regulation of muscle contractions and is composed of a series of subunits that interact with one another to control the movement of muscle cells.

FERMT1 plays a critical role in the regulation of myosin activity by interacting with the myosin protein and the related protein called myosin regulatory protein (MyRP). MyRP is a protein that is involved in the regulation of myosin activity and is composed of a series of subunits that interact with one another to control the position of the myosin heads at the tips of the myosin filaments.

FERMT1 is able to interact with MyRP by a process called phosphorylation, which involves the addition of a phosphate group to a specific amino acid residue on the protein. This interaction between FERMT1 and MyRP is important for the regulation of myosin activity and is involved in a wide range of physiological processes in the body, including muscle contractions and the regulation of cell growth and division.

One of the potential benefits of targeting FERMT1 as a drug or biomarker is its ability to interact with multiple proteins and to be involved in a wide range of physiological processes. This makes it an attractive target for researchers who are interested in the regulation of myosin activity and the role of this protein in various physiological processes.

In addition to its role in the regulation of myosin activity, FERMT1 is also involved in the regulation of a variety of other cellular processes, including cell adhesion, cell signaling, and the regulation of ion channels. This makes it an important protein that should be carefully studied in order to gain a better understanding of its role in various physiological processes.

Overall, FERMT1 is a unique and important protein that is involved in the regulation of myosin activity and has a wide range of potential applications as a drug or biomarker. Further research is needed to fully understand the role of this protein in various physiological processes and to explore its potential as a therapeutic agent.

Protein Name: FERM Domain Containing Kindlin 1

Functions: Involved in cell adhesion. Contributes to integrin activation. When coexpressed with talin, potentiates activation of ITGA2B. Required for normal keratinocyte proliferation. Required for normal polarization of basal keratinocytes in skin, and for normal cell shape. Required for normal adhesion of keratinocytes to fibronectin and laminin, and for normal keratinocyte migration to wound sites. May mediate TGF-beta 1 signaling in tumor progression

More Common Targets

FERMT2 | FERMT3 | Ferritin | FES | Fetal Hemoglobin (HbF) | FETUB | FEV | FEZ1 | FEZ2 | FEZF1 | FEZF1-AS1 | FEZF2 | FFAR1 | FFAR2 | FFAR3 | FFAR4 | FGA | FGB | FGD1 | FGD2 | FGD3 | FGD4 | FGD5 | FGD5-AS1 | FGD5P1 | FGD6 | FGF1 | FGF10 | FGF10-AS1 | FGF11 | FGF12 | FGF12-AS2 | FGF13 | FGF13-AS1 | FGF14 | FGF14-AS1 | FGF14-AS2 | FGF14-IT1 | FGF16 | FGF17 | FGF18 | FGF19 | FGF2 | FGF20 | FGF21 | FGF22 | FGF23 | FGF3 | FGF4 | FGF5 | FGF6 | FGF7 | FGF7P3 | FGF7P5 | FGF7P6 | FGF8 | FGF9 | FGFBP1 | FGFBP2 | FGFBP3 | FGFR1 | FGFR1OP2 | FGFR2 | FGFR3 | FGFR3P1 | FGFR4 | FGFRL1 | FGG | FGGY | FGL1 | FGL2 | FGR | FH | FHAD1 | FHDC1 | FHF Complex | FHIP1A | FHIP1B | FHIP2A | FHIP2B | FHIT | FHL1 | FHL2 | FHL3 | FHL5 | FHOD1 | FHOD3 | FIBCD1 | FIBIN | FIBP | Fibrinogen | Fibroblast growth factor (FGF) | Fibroblast Growth Factor Receptor (FGFR) | Fibronectin Type III Domain | FICD | FIG4 | FIGLA | FIGN | FIGNL1 | FIGNL2