FGFRL1: A Potential Drug Target and Biomarker (G53834)
FGFRL1: A Potential Drug Target and Biomarker
Fibroblast growth factor receptor-like 1 (FGFRL1) is a protein that is expressed in various tissues, including skin, hair, and nails. It is a member of the FGF receptor family, which is a subset of the TGF-β superfamily. FGFRL1 has been shown to play a role in the regulation of cellular processes such as cell growth, differentiation, and inflammation.
Recent studies have identified FGFRL1 as a potential drug target in the treatment of various diseases, including cancer, wound healing, and skin diseases. Its role in these processes makes it an attractive target for drug development due to its potential to modulate cellular behavior and stimulate therapeutic responses.
One of the key advantages of FGFRL1 as a drug target is its expressed status in a wide range of tissues, making it a potentially applicable target for both intravascular and systemic treatments. For example, FGFRL1 has been shown to be highly expressed in various types of cancer, including breast, ovarian, and colorectal cancers. This makes it a promising target for cancer therapies that aim to inhibit FGFRL1 signaling.
In addition to its potential as a cancer therapeutic, FGFRL1 has also been identified as a potential biomarker for the diagnosis and monitoring of various diseases. For example, FGFRL1 has been shown to be expressed in the skin, hair, and nails of individuals with conditions such as diabetes, wound healing, and autoimmune disorders. This makes it a potential indicator of disease severity and an effective biomarker for monitoring the effectiveness of therapeutic interventions.
FGFRL1 has also been shown to play a role in the regulation of cellular processes that are important for wound healing and tissue regeneration. Its expression has been shown to promote the migration of cells to the site of injury and stimulate the production of extracellular matrix (ECM) components, such as collagen and hyaluronic acid, which are critical for tissue regeneration.
In conclusion, FGFRL1 is a protein that has the potential to be a drug target and biomarker in a wide range of diseases. Its expressed status in various tissues and its role in the regulation of cellular processes make it an attractive target for drug development. Further research is needed to fully understand the mechanisms of FGFRL1 and its potential as a drug and biomarker.
Protein Name: Fibroblast Growth Factor Receptor Like 1
Functions: Has a negative effect on cell proliferation
More Common Targets
FGG | FGGY | FGL1 | FGL2 | FGR | FH | FHAD1 | FHDC1 | FHF Complex | FHIP1A | FHIP1B | FHIP2A | FHIP2B | FHIT | FHL1 | FHL2 | FHL3 | FHL5 | FHOD1 | FHOD3 | FIBCD1 | FIBIN | FIBP | Fibrinogen | Fibroblast growth factor (FGF) | Fibroblast Growth Factor Receptor (FGFR) | Fibronectin Type III Domain | FICD | FIG4 | FIGLA | FIGN | FIGNL1 | FIGNL2 | FILIP1 | FILIP1L | FILNC1 | FIP1L1 | FIRRE | FIS1 | FITM1 | FITM2 | Five friends of methylated CHTOP complex | FIZ1 | FJX1 | FKBP10 | FKBP11 | FKBP14 | FKBP15 | FKBP1A | FKBP1A-SDCBP2 | FKBP1B | FKBP1C | FKBP2 | FKBP3 | FKBP4 | FKBP5 | FKBP6 | FKBP7 | FKBP8 | FKBP9 | FKBP9P1 | FKBPL | FKRP | FKSG29 | FKTN | FLACC1 | FLAD1 | FLCN | FLG | FLG-AS1 | FLG2 | FLI1 | FLII | FLJ12825 | FLJ13224 | FLJ16779 | FLJ20021 | FLJ20712 | FLJ25758 | FLJ30679 | FLJ31945 | FLJ32154 | FLJ32255 | FLJ33534 | FLJ36000 | FLJ37201 | FLJ37786 | FLJ38576 | FLJ39095 | FLJ40194 | FLJ42393 | FLJ42627 | FLJ42969 | FLJ43315 | FLJ44342 | FLJ44635 | FLJ45513 | FLJ46875 | FLNA | FLNB
