Target Name: FILIP1
NCBI ID: G27145
Other Name(s): FLIP1_HUMAN | Filamin-A-interacting protein 1 (isoform 2) | Filamin A interacting protein 1 | filamin A interacting protein 1 | FILIP | FILIP1 variant 2 | KIAA1275 | Filamin-A-interacting protein 1 | Filamin A interacting protein 1, transcript variant 2

Understanding FILIP1: A Potential Drug Target Or Biomarker

FILIP1 (FLIP1_HUMAN), a gene that encodes a protein known as FILIP1, has been identified as a potential drug target or biomarker for various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. Its unique structure and function have made it an attractive target for researchers to study and develop new treatments.

The FILIP1 gene was identified in the human genome as a key regulator of cell signaling pathways, particularly in the regulation of cell adhesion and migration. The FILIP1 protein plays a crucial role in the formation of tight junctions, which are a type of cell-cell adhesion that helps to maintain tissue structure and function.

FILIP1 has been shown to be involved in various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. For example, studies have shown that high levels of FILIP1 are associated with an increased risk of colorectal cancer, and that FILIP1 may also play a role in the development of neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease.

FILIP1 has also been shown to be involved in autoimmune disorders, such as rheumatoid arthritis and multiple sclerosis. In these disorders, the immune system attacks the body's own tissues, leading to inflammation and damage. FILIP1 has been shown to be involved in the regulation of immune cell function, and may play a role in the development and progression of autoimmune disorders.

Despite the potential benefits of FILIP1 as a drug target or biomarker, much more research is needed to fully understand its function and potential risks. For example, researchers are still studying the exact mechanism by which FILIP1 promotes cancer growth and the development of neurodegenerative diseases.

In addition, there are concerns about the potential side effects of targeting FILIP1, as similar proteins have been shown to cause various adverse reactions in humans. For example, a drug that targets a related protein called FILIP4 was shown to cause severe side effects such as nausea, vomiting, and muscle breakdown.

Despite these challenges, researchers are still actively studying FILIP1 and its potential as a drug target or biomarker. With further research, FILIP1 may prove to be a valuable tool for the development of new treatments for a variety of diseases.

Protein Name: Filamin A Interacting Protein 1

Functions: By acting through a filamin-A/F-actin axis, it controls the start of neocortical cell migration from the ventricular zone. May be able to induce the degradation of filamin-A

More Common Targets

FILIP1L | FILNC1 | FIP1L1 | FIRRE | FIS1 | FITM1 | FITM2 | Five friends of methylated CHTOP complex | FIZ1 | FJX1 | FKBP10 | FKBP11 | FKBP14 | FKBP15 | FKBP1A | FKBP1A-SDCBP2 | FKBP1B | FKBP1C | FKBP2 | FKBP3 | FKBP4 | FKBP5 | FKBP6 | FKBP7 | FKBP8 | FKBP9 | FKBP9P1 | FKBPL | FKRP | FKSG29 | FKTN | FLACC1 | FLAD1 | FLCN | FLG | FLG-AS1 | FLG2 | FLI1 | FLII | FLJ12825 | FLJ13224 | FLJ16779 | FLJ20021 | FLJ20712 | FLJ25758 | FLJ30679 | FLJ31945 | FLJ32154 | FLJ32255 | FLJ33534 | FLJ36000 | FLJ37201 | FLJ37786 | FLJ38576 | FLJ39095 | FLJ40194 | FLJ42393 | FLJ42627 | FLJ42969 | FLJ43315 | FLJ44342 | FLJ44635 | FLJ45513 | FLJ46875 | FLNA | FLNB | FLNC | FLOT1 | FLOT2 | FLRT1 | FLRT2 | FLRT3 | FLT1 | FLT3 | FLT3LG | FLT4 | FLVCR1 | FLVCR1-DT | FLVCR2 | FLVCR2-AS1 | FLYWCH1 | FLYWCH2 | FMC1 | FMC1-LUC7L2 | FMN1 | FMN2 | FMNL1 | FMNL2 | FMNL3 | FMO1 | FMO2 | FMO3 | FMO4 | FMO5 | FMO6P | FMO9P | FMOD | FMR1 | FMR1-AS1 | FMR1NB