FLOT1: A Protein with Potential as a Drug Target and Biomarker

Target Name: FLOT1

NCBI ID: G10211

FLOT1: A Protein with Potential as a Drug Target and Biomarker

FLOT1 (Flotillin-1 (isoform 1)) is a protein that is expressed in various tissues throughout the body, including the placenta, liver, and kidneys. It is a member of the flotillin family, which is characterized by the presence of a hydrophobic domain that is responsible for the protein's ability to form a millimeter-scale flotome.

FLOT1 is a key regulator of cell adhesion and migration, as well as the formation of blood vessels and the regulation of inflammation. It is involved in the development and maintenance of tissues and organs, including the placenta and the immune system.

FLOT1 has also been shown to play a role in the regulation of cancer cell growth and the development of certain diseases, such as heart disease and neurodegenerative disorders. It is also a potential drug target, with several studies suggesting that FLOT1 may be a promising target for the development of new treatments for these conditions.

One of the key advantages of FLOT1 as a drug target is its expression in a wide range of tissues, which makes it relatively easy to study and target. It is also a small protein, which makes it relatively easy to synthesize and deliver to the body.

FLOT1 has been shown to play a role in the regulation of several key signaling pathways, including the NF-kappa pathway and the Wnt pathway. This makes it a potential target for drugs that target these pathways.

In addition to its potential as a drug target, FLOT1 is also a potential biomarker for several diseases. Its expression has been shown to be elevated in a variety of diseases, including cancer, neurodegenerative disorders, and autoimmune diseases. This makes it a potential indicator of the severity of these conditions and a useful diagnostic tool.

FLOT1 is also a potential target for drug development due to its unique structure and function. Its hydrophobic domain allows it to form a stable millimeter-scale flotome, which is not typically found in other proteins. This allows it to interact with a wide range of molecules and be targeted by a variety of drugs.

Overall, FLOT1 is a protein that has significant potential as a drug target and biomarker. Its unique structure and function make it an attractive target for research and development of new treatments for a wide range of diseases.

Protein Name: Flotillin 1

Functions: May act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles

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