Target Name: FLNB
NCBI ID: G2317
Other Name(s): Filamin-3 | TABP | Actin-binding-like protein | filamin-3 | FLN1L | thyroid autoantigen | AOI | ABP-280 | SCT | Truncated ABP | TAP | FLNB variant 2 | Filamin homolog 1 | Thyroid autoantigen | filamin B | FLNB variant 1 | FLN-B | Filamin B | filamin B, beta | actin-binding-like protein | ABP-280 homolog | beta-filamin | filamin homolog 1 | FLNB_HUMAN | Larsen syndrome 1 (autosomal dominant) | Filamin B, transcript variant 1 | LRS1 | Filamin B, transcript variant 2 | Truncated actin-binding protein | Filamin-B | ABP-278 | FH1 | Fh1 | actin binding protein 278 | Beta-filamin

FLNB: A Protein Involved in Cell Division, Migration and Signaling

FLNB (Filamin-3) is a protein that is expressed in various tissues of the body, including the nervous system, muscle system, and endocrine system. It is a key component of the cytoskeleton, which is the structure that gives shape to the cells of the body.

FLNB has been shown to play a role in the regulation of cell division and the development of various diseases, including cancer. It is also a potential drug target for several diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

One of the key functions of FLNB is its role in the regulation of cell division. During cell division, FLNB helps to ensure that the cell divides into two daughter cells that are identical, each carrying the same genetic information. This helps to maintain the integrity of the cell and prevent errors from occurring during cell division.

FLNB is also involved in the regulation of cell migration, which is the movement of cells towards specific locations in the body. This is important for the development and maintenance of tissues and organs, as well as for the formation of new blood vessels.

In addition to its role in cell division and migration, FLNB has also been shown to play a role in the regulation of cell signaling. It is a signaling molecule that can interact with a variety of different proteins, including those that are involved in the regulation of cell growth, differentiation, and survival.

FLNB has been shown to be involved in the development of several diseases, including cancer. For example, studies have shown that FLNB is often expressed in tissues of cancerous cells, and that it plays a role in the regulation of cell division and the development of cancer.

FLNB is also a potential drug target for several other diseases, including neurodegenerative disorders and autoimmune disorders. For example, studies have shown that FLNB is involved in the development of neurodegenerative disorders, such as Alzheimer's disease and Parkinson's disease, and that it may be a potential drug target for these disorders.

In addition to its potential as a drug target, FLNB is also of interest as a biomarker for several diseases. For example, studies have shown that FLNB is often expressed in the brains of individuals with Alzheimer's disease, and that it may be a potential biomarker for this disorder.

Overall, FLNB is a protein that is expressed in various tissues of the body and is involved in several important functions, including cell division, migration, and signaling. Its potential as a drug target and biomarker makes it an attractive target for further research and development.

Protein Name: Filamin B

Functions: Connects cell membrane constituents to the actin cytoskeleton. May promote orthogonal branching of actin filaments and links actin filaments to membrane glycoproteins. Anchors various transmembrane proteins to the actin cytoskeleton. Interaction with FLNA may allow neuroblast migration from the ventricular zone into the cortical plate. Various interactions and localizations of isoforms affect myotube morphology and myogenesis. Isoform 6 accelerates muscle differentiation in vitro

More Common Targets

FLNC | FLOT1 | FLOT2 | FLRT1 | FLRT2 | FLRT3 | FLT1 | FLT3 | FLT3LG | FLT4 | FLVCR1 | FLVCR1-DT | FLVCR2 | FLVCR2-AS1 | FLYWCH1 | FLYWCH2 | FMC1 | FMC1-LUC7L2 | FMN1 | FMN2 | FMNL1 | FMNL2 | FMNL3 | FMO1 | FMO2 | FMO3 | FMO4 | FMO5 | FMO6P | FMO9P | FMOD | FMR1 | FMR1-AS1 | FMR1NB | FN1 | FN3K | FN3KRP | FNBP1 | FNBP1L | FNBP1P1 | FNBP4 | FNDC1 | FNDC10 | FNDC11 | FNDC3A | FNDC3B | FNDC4 | FNDC5 | FNDC7 | FNDC8 | FNDC9 | FNIP1 | FNIP2 | FNTA | FNTB | FOCAD | Focal Adhesion Kinases (FAK) | Folate Receptor | FOLH1 | FOLH1B | Follicle stimulating hormone | FOLR1 | FOLR2 | FOLR3 | Formin homology 2 domain-containing proteins | FOS | FOSB | FOSL1 | FOSL2 | FOSL2-AS1 | FOXA1 | FOXA2 | FOXA3 | FOXB1 | FOXB2 | FOXC1 | FOXC2 | FOXC2-AS1 | FOXCUT | FOXD1 | FOXD2 | FOXD2-AS1 | FOXD3 | FOXD3-AS1 | FOXD4 | FOXD4L1 | FOXD4L3 | FOXD4L4 | FOXD4L5 | FOXD4L6 | FOXE1 | FOXE3 | FOXF1 | FOXF2 | FOXF2-DT | FOXG1 | FOXG1-AS1 | FOXH1 | FOXI1 | FOXI2