IMPDH1P10: A Promising Drug Target / Biomarker (G100874399)
IMPDH1P10: A Promising Drug Target / Biomarker
IMPDH1P10 is a protein that is expressed in various tissues throughout the body. It is a key regulator of the inter-cellular signaling pathway known as the insulin-like growth factor (IGF) signaling pathway. This pathway plays a crucial role in the development, maintenance, and regulation of tissues, including muscles, bones, and organs. It is also involved in the regulation of cellular processes such as cell growth, differentiation, and survival.
The IMPDH1P10 protein has been identified as a potential drug target or biomarker for various diseases, including cancer, obesity, and neurodegenerative diseases. This is due to its involvement in the IGF signaling pathway, which is often disrupted in these conditions.
The IGF signaling pathway is a critical regulator of cellular processes that promote growth, differentiation, and survival. It is composed of several transcription factors, including SMAD1, SMAD4, and FGF1. These transcription factors bind to specific DNA sequences to regulate the expression of target genes, including IMPDH1P10.
IMPDH1P10 is a key regulator of the IGF signaling pathway. It is a 21-kDa protein that is expressed in various tissues, including muscle, liver, and brain. It is highly conserved and has a similar structure to other members of the IMPDH family, which includes IMPDH2 and IMPDH3.
IMPDH1P10 functions as a negative regulator of the IGF signaling pathway. It binds to the SMAD receptor, which is a transmembrane protein that is composed of two distinct subunits. This interaction between IMPDH1P10 and SMAD leads to the inhibition of SMAD2, which is the transcription factor that activates the IGF signaling pathway.
The IGF signaling pathway is involved in the regulation of cellular processes that are critical for human growth and development. It is involved in the development and maintenance of tissues, including muscles, bones, and organs. It is also involved in the regulation of cellular processes such as cell growth, differentiation, and survival.
IMPDH1P10 is a key regulator of the IGF signaling pathway. It is involved in the regulation of cellular processes that are critical for human growth and development. It is a potential drug target or biomarker for various diseases, including cancer, obesity, and neurodegenerative diseases.
Conclusion
IMPDH1P10 is a protein that is involved in the regulation of the IGF signaling pathway. It is a key regulator of this pathway and plays a crucial role in the development, maintenance, and regulation of tissues. It is also involved in the regulation of cellular processes such as cell growth, differentiation, and survival.
IMPDH1P10 is a potential drug target or biomarker for various diseases, including cancer, obesity, and neurodegenerative diseases. Its involvement in the IGF signaling pathway makes it an attractive target for the development of new treatments for these conditions. Further research is needed to fully understand the role of IMPDH1P10 in the regulation of IGF signaling and its potential as a drug target.
Protein Name: Inosine Monophosphate Dehydrogenase 1 Pseudogene 10
More Common Targets
IMPDH1P6 | IMPDH2 | IMPG1 | IMPG2 | INA | INAFM1 | INAFM2 | INAVA | INCA1 | INCENP | INE1 | INE2 | INF2 | ING1 | ING2 | ING2-DT | ING3 | ING4 | ING5 | INGX | INHA | INHBA | INHBA-AS1 | INHBB | INHBC | INHBE | INHCAP | Inhibitor of Apoptosis Proteins (IAPs) | Inhibitory kappaB Kinase (IKK) | INIP | INKA1 | INKA2 | INKA2-AS1 | INMT | INMT-MINDY4 | Innate Repair Receptor (IRR) | INO80 | INO80 complex | INO80B | INO80B-WBP1 | INO80C | INO80D | INO80E | Inositol 1,4,5-Trisphosphate Receptor (InsP3R) | Inositol hexakisphosphate kinase | Inositol Monophosphatase | INPP1 | INPP4A | INPP4B | INPP5A | INPP5B | INPP5D | INPP5E | INPP5F | INPP5J | INPP5K | INPPL1 | INS | INS-IGF2 | INSC | INSIG1 | INSIG2 | INSL3 | INSL4 | INSL5 | INSL6 | INSM1 | INSM2 | INSR | INSRR | Insulin-like growth factor | Insulin-like growth factor 2 mRNA binding protein | Insulin-like growth factor 2 mRNA-binding protein 1 (isoform 2) | Insulin-like growth factor-binding protein | INSYN1 | INSYN2A | INSYN2B | Integrator complex | Integrin alpha1beta1 (VLA-1) receptor | Integrin alpha2beta1 (VLA-2) receptor | Integrin alpha2beta3 Receptor | Integrin alpha3beta1 receptor | Integrin alpha4beta1 (VLA-4) receptor | Integrin alpha4beta7 (LPAM-1) receptor | Integrin alpha5beta1 (VLA-5) receptor | Integrin alpha5beta3 receptor | Integrin alpha6beta1 Receptor | Integrin alpha6beta4 receptor | Integrin alpha7beta1 Receptor | Integrin alpha9beta1 receptor | Integrin alphaEbeta7 receptor | Integrin alphaLbeta2 (LFA-1) receptor | Integrin alphaMbeta2 (MAC-1) Receptor | Integrin alphavbeta1 | Integrin alphavbeta3 (vitronectin) receptor | Integrin alphavbeta5 receptor | Integrin alphavbeta6 receptor | Integrin alphavbeta8 Receptor | Integrin Receptor | Integrin-linked kinase