Understanding The Role of Integrin Alpha7beta1 Receptor (P32803)

Target Name: Integrin alpha7beta1 Receptor

NCBI ID: P32803

Other Name(s): None

Understanding The Role of Integrin Alpha7beta1 Receptor

Integrin alpha7beta1 receptor, also known as ITGA7 or CD73, is a protein that is expressed in various tissues throughout the body. It plays a crucial role in cell-cell adhesion, which is the process by which cells stick together to form tissues and organs.

Integrin alpha7beta1 receptor is a transmembrane protein that is composed of an extracellular domain, a transmembrane region, and an intracellular domain. The extracellular domain is involved in cell adhesion, while the transmembrane region plays a role in the receptor's cytoskeletal structure and stability. The intracellular domain is responsible for the receptor's interaction with intracellular signaling molecules, such as tyrosines and serines.

One of the most significant functions of Integrin alpha7beta1 receptor is its role in cancer progression. It has been shown to be involved in the development and progression of various cancers, including breast, ovarian, and colorectal cancers.

Research has also shown that Integrin alpha7beta1 receptor is involved in the regulation of pain perception. It has been shown to play a role in the modulation of pain by neurotransmitters, such as serotonin and norepinephrine.

Another potential drug target for Integrin alpha7beta1 receptor is its role in the regulation of inflammation. It has been shown to be involved in the regulation of inflammation by T cells, which are a crucial immune cell that play a role in protecting the body against infection and disease.

Integrin alpha7beta1 receptor has also been shown to be involved in the regulation of stem cell proliferation. It has been shown to play a role in the regulation of stem cell self-renewal and differentiation, which are important processes for the development and maintenance of tissues and organs.

In conclusion, Integrin alpha7beta1 receptor is a protein that is involved in a wide range of physiological processes in the body. Its role in cell-cell adhesion, cancer progression, pain perception, inflammation, and stem cell proliferation make it an attractive drug target for researchers. Further research is needed to fully understand the mechanisms of Integrin alpha7beta1 receptor and its potential as a drug target.

Protein Name: Integrin Alpha7beta1 Receptor

More Common Targets