KRT18P6: A Potential Drug Target and Biomarker (G122592)
KRT18P6: A Potential Drug Target and Biomarker
Keratin 18 pseudogene 6 (KRT18P6) is a gene that has been identified as a potential drug target in the field of skin diseases. The gene is located on chromosome 16 and encodes a protein known as keratin 18 (K18), which is a key component of the hair and nail. K18 is known to play a role in the regulation of cell growth, differentiation, and survival, and is implicated in a number of skin diseases, including tanning disorders, alopecia areata, and skin cancer.
Recent studies have suggested that KRT18P6 may be a promising drug target for the treatment of skin diseases due to its involvement in the regulation of hair and nail growth and its potential role in the development of these diseases. In particular, KRT18P6 has been shown to be highly expressed in skin tissues and has been implicated in the development of various skin diseases, including tanning disorders and alopecia areata.
In tanning disorders, KRT18P6 has been shown to contribute to the development of hyperpigmentation, a condition in which the skin takes on a brown or black color. This is thought to occur due to the activation of the gene, which results in the production of excess melanin. In addition, KRT18P6 has also been shown to be involved in the regulation of cell growth and differentiation, which may play a role in the development of other skin diseases.
Alopecia areata is a genetic disorder that is characterized by the loss of hair in patches. The exact cause of alopecia areata is not known, but it is thought to involve a combination of genetic and environmental factors. KRT18P6 has been shown to be involved in the regulation of hair growth and differentiation, and may be a potential drug target for the treatment of this disorder.
In addition to its potential role in the development of tanning disorders and alopecia areata, KRT18P6 has also been implicated in the development of skin cancer. The gene has been shown to be involved in the regulation of cell growth and differentiation, which may play a role in the development of cancer. This suggests that KRT18P6 may be a potential drug target for the treatment of skin cancer.
Overall, KRT18P6 is a gene that has the potential to be a drug target for the treatment of skin diseases. Its involvement in the regulation of hair and nail growth, as well as its potential role in the development of tanning disorders, alopecia areata, and skin cancer, make it a promising target for researchers to investigate further. Further studies are needed to fully understand the role of KRT18P6 in these diseases and to develop effective treatments.
Protein Name: Keratin 18 Pseudogene 6
More Common Targets
KRT18P62 | KRT19 | KRT19P2 | KRT19P3 | KRT2 | KRT20 | KRT222 | KRT23 | KRT24 | KRT25 | KRT26 | KRT27 | KRT28 | KRT3 | KRT31 | KRT32 | KRT33A | KRT33B | KRT34 | KRT35 | KRT36 | KRT37 | KRT38 | KRT39 | KRT4 | KRT40 | KRT42P | KRT5 | KRT6A | KRT6B | KRT6C | KRT7 | KRT7-AS | KRT71 | KRT72 | KRT73 | KRT73-AS1 | KRT74 | KRT75 | KRT76 | KRT77 | KRT78 | KRT79 | KRT8 | KRT80 | KRT81 | KRT82 | KRT83 | KRT84 | KRT85 | KRT86 | KRT87P | KRT89P | KRT8P10 | KRT8P11 | KRT8P12 | KRT8P14 | KRT8P16 | KRT8P17 | KRT8P18 | KRT8P22 | KRT8P23 | KRT8P25 | KRT8P26 | KRT8P29 | KRT8P3 | KRT8P33 | KRT8P36 | KRT8P37 | KRT8P39 | KRT8P41 | KRT8P44 | KRT8P45 | KRT8P46 | KRT8P47 | KRT8P48 | KRT8P49 | KRT8P5 | KRT8P7 | KRT8P8 | KRT8P9 | KRT9 | KRT90P | KRTAP1-1 | KRTAP1-3 | KRTAP1-4 | KRTAP1-5 | KRTAP10-1 | KRTAP10-10 | KRTAP10-11 | KRTAP10-12 | KRTAP10-2 | KRTAP10-3 | KRTAP10-4 | KRTAP10-5 | KRTAP10-6 | KRTAP10-7 | KRTAP10-8 | KRTAP10-9 | KRTAP11-1