KRT5: Potential Drug Target and Biomarker (G3852)

Target Name: KRT5

NCBI ID: G3852

KRT5: Potential Drug Target and Biomarker

KRT5 (keratin 5) is a protein that is expressed in a variety of tissues throughout the body, including hair, nails, and skin. It is a key component of the cytoskeleton, which is the structure that gives cells their shape and helps them maintain their shape during growth and development.

Recent studies have suggested that KRT5 may have a variety of potential applications as a drug target or biomarker.

One potential application of KRT5 as a drug target is its role in the development of cancer. Studies have shown that KRT5 is often overexpressed in a variety of cancer types, which suggests that targeting KRT5 may be a promising strategy for cancer treatment.

Another potential application of KRT5 as a drug target is its role in the development of skin diseases. For example, research has shown that KRT5 is overexpressed in a variety of skin conditions, including acne and psoriasis. Targeting KRT5 with drugs that can suppress its expression may be a promising strategy for treating these conditions.

In addition to its potential as a drug target, KRT5 has also been suggested as a potential biomarker for a variety of diseases. For example, KRT5 has been shown to be overexpressed in a variety of skin conditions, including acne and psoriasis. This suggests that KRT5 may be a useful biomarker for these conditions.

Overall, KRT5 is a protein that is expressed in a variety of tissues throughout the body and has been suggested as a potential drug target or biomarker in a variety of conditions. Further research is needed to fully understand its potential applications and to develop treatments based on it.

Protein Name: Keratin 5

Functions: Required for the formation of keratin intermediate filaments in the basal epidermis and maintenance of the skin barrier in response to mechanical stress (By similarity). Regulates the recruitment of Langerhans cells to the epidermis, potentially by modulation of the abundance of macrophage chemotactic cytokines, macrophage inflammatory cytokines and CTNND1 localization in keratinocytes (By similarity)

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