KRTAP20-2: A Potential Drug Target and Biomarker (G337976)

Target Name: KRTAP20-2

NCBI ID: G337976

Other Name(s): Keratin associated protein 20-2 | Keratin-associated protein 20-2 | KR202_HUMAN | KAP20.2 | keratin associated protein 20-2

KRTAP20-2: A Potential Drug Target and Biomarker

Keratin associated protein 20-2 (KRTAP20-2) is a protein that has been identified as a potential drug target and biomarker in the field of skin diseases. KRTAP20-2 is a member of the keratin family, which is a well-known family of proteins that are involved in the structure and function of hair and nails. The discovery and characterization of KRTAP20-2 has significant implications for the development of new treatments for a variety of skin diseases.

The Skin and Hair

The skin and hair are two of the most important organs in the body. The skin is responsible for protecting the body from external threats, while the hair plays a critical role in maintaining the body's temperature and preventing heat loss. Both the skin and hair are composed of proteins, which are essential for their structure and function.

KRTAP20-2 is a protein that is expressed in the skin and hair, and it is involved in the development and maintenance of these structures. The discovery of KRTAP20-2 as a potential drug target and biomarker has significant implications for the treatment of skin diseases.

The Drug Target

KRTAP20-2 has been shown to be involved in a variety of skin diseases, including actinic dermatitis, seborrheic dermatitis, and psoriasis. These conditions are characterized by inflammation, itching, and the appearance of skin symptoms. KRTAP20-2 has been shown to play a role in the development and progression of these conditions, which suggests that it may be a useful target for new treatments.

The Biomarker

In addition to its role in skin diseases, KRTAP20-2 has also been shown to be involved in the development and progression of certain types of cancer. This suggests that it may be a potential biomarker for cancer, and that its levels may be an important indicator of the disease.

The Discovery and Characterization of KRTAP20-2

KRTAP20-2 was first identified by researchers using mass spectrometry, which is a technique that involves the separation and identification of proteins based on their amino acid sequence. The protein was shown to be expressed in the skin and hair, and it was shown to play a role in the development and progression of skin diseases.

Subsequent studies have demonstrated the effectiveness of targeting KRTAP20-2 with small molecules, which have been shown to inhibit the activity of the protein. These studies have implications for the development of new treatments for skin diseases.

The Potential Applications of KRTAP20-2 as a Drug Target

The discovery of KRTAP20-2 as a potential drug target has significant implications for the treatment of skin diseases. By inhibiting the activity of KRTAP20-2, new treatments can be developed that will provide relief from symptoms and improve the quality of life for people with skin diseases.

In addition to its potential as a drug target, KRTAP20-2 has also been shown to be involved in the development and progression of certain types of cancer. This suggests that it may be a potential biomarker for cancer, and that its levels may be an important indicator of the disease.

The Future of KRTAP20-2

The discovery of KRTAP20-2 has significant implications for the treatment of skin diseases and the development of new treatments for cancer. Further research is needed to fully understand the role of KRTAP20-2 in these conditions and to develop effective new treatments.

Conclusion

KRTAP20-2 is a protein that is expressed in the skin and hair and is involved in the development and maintenance of these structures. Its potential as a drug target and biomarker for skin diseases and cancer makes it an attractive target for

Protein Name: Keratin Associated Protein 20-2

Functions: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins

More Common Targets