KRTAP17-1: A Potential Drug Target and Biomarker (G83902)
KRTAP17-1: A Potential Drug Target and Biomarker
Keratin-associated protein 17-1 (KRTAP17-1) is a protein that has been identified as a potential drug target and biomarker for various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. Its unique structure and subcellular localization make it an attractive target for small molecule inhibitors. In this article, we will discuss the research on KRTAP17-1, its potential drug target status, and its potential as a biomarker for various diseases.
Structure and Localization
KRTAP17-1 is a 21-kDa protein that is expressed in various tissues, including hair, skin, and nails. It is highly expressed in tissues that are sensitive to damage, such as the skin and the nervous system. KRTAP17-1 is localized to the peripodial region of the skin and is involved in the regulation of cell growth, differentiation, and survival.
KRTAP17-1 is a member of the keratin family, which is known for its role in the development and maintenance of hair and skin. It is part of the A protein family, which is characterized by the presence of a specific N-terminal domain and a C-terminus that is involved in protein-protein interactions.
Expression and Localization
KRTAP17-1 is highly expressed in various tissues, including the skin, hair, and nervous system. It is expressed in the peripodial tissue of the skin and is involved in the regulation of cell growth, differentiation, and survival. KRTAP17-1 is also expressed in the nervous system, including the brain, where it is involved in the regulation of neuronal communication and cell survival.
In addition to its expression in various tissues, KRTAP17-1 is also localized to specific cellular compartments. It is located in the peripodial tissue of the skin and is involved in the regulation of cell growth, differentiation, and survival. KRTAP17-1 is also associated with the endoplasmic reticulum (ER) and is involved in the regulation of protein translation and localization to various cellular compartments.
Potential Drug Target
KRTAP17-1 is a protein that has been identified as a potential drug target for various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. Its unique structure and subcellular localization make it an attractive target for small molecule inhibitors.
One of the potential reasons for the potential drug target status of KRTAP17-1 is its involvement in the regulation of cell growth and differentiation. KRTAP17-1 has been shown to play a role in the regulation of cell growth and has been shown to be involved in the regulation of cell differentiation.
In addition to its involvement in cell growth and differentiation, KRTAP17-1 has also been shown to be involved in the regulation of cell survival. KRTAP17-1 has been shown to play a role in the regulation of cell survival and has been shown to be involved in the regulation of cell apoptosis.
Potential Biomarker
In addition to its potential as a drug target, KRTAP17-1 has also been identified as a potential biomarker for various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. Its unique structure and subcellular localization make it an attractive target for small molecule inhibitors.
One of the potential reasons for its potential as a biomarker is its involvement in the regulation of cell growth and differentiation. KRTAP17-1 has been shown to play a role in the regulation of cell growth and has been shown to have
Protein Name: Keratin Associated Protein 17-1
Functions: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins
More Common Targets
KRTAP19-1 | KRTAP19-2 | KRTAP19-3 | KRTAP19-4 | KRTAP19-5 | KRTAP19-6 | KRTAP19-7 | KRTAP19-8 | KRTAP2-1 | KRTAP2-2 | KRTAP2-3 | KRTAP2-4 | KRTAP20-1 | KRTAP20-2 | KRTAP20-3 | KRTAP20-4 | KRTAP21-1 | KRTAP21-2 | KRTAP21-3 | KRTAP22-1 | KRTAP22-2 | KRTAP23-1 | KRTAP25-1 | KRTAP26-1 | KRTAP27-1 | KRTAP29-1 | KRTAP3-1 | KRTAP3-2 | KRTAP3-3 | KRTAP4-1 | KRTAP4-11 | KRTAP4-12 | KRTAP4-2 | KRTAP4-3 | KRTAP4-4 | KRTAP4-5 | KRTAP4-6 | KRTAP4-7 | KRTAP4-8 | KRTAP4-9 | KRTAP5-1 | KRTAP5-10 | KRTAP5-11 | KRTAP5-14P | KRTAP5-2 | KRTAP5-3 | KRTAP5-4 | KRTAP5-5 | KRTAP5-7 | KRTAP5-8 | KRTAP5-9 | KRTAP5-AS1 | KRTAP6-1 | KRTAP6-2 | KRTAP6-3 | KRTAP7-1 | KRTAP8-1 | KRTAP9-1 | KRTAP9-2 | KRTAP9-3 | KRTAP9-4 | KRTAP9-6 | KRTAP9-7 | KRTAP9-8 | KRTAP9-9 | KRTCAP2 | KRTCAP3 | KRTDAP | KSR1 | KSR1P1 | KSR2 | KTI12 | KTN1 | KTN1-AS1 | KXD1 | KY | KYAT1 | KYAT3 | KYNU | L-Type calcium channel | L-type voltage-dependent calcium channel complex | L1CAM | L1CAM-AS1 | L1TD1 | L2HGDH | L3HYPDH | L3MBTL1 | L3MBTL2 | L3MBTL3 | L3MBTL4 | L3MBTL4-AS1 | LACAT1 | LACC1 | LACRT | Lactate Dehydrogenase (LDH) | LACTB | LACTB2 | LACTB2-AS1 | LACTBL1 | LAD1