KRTAP10-12: A Potential Drug Target and Biomarker (G386685)

Target Name: KRTAP10-12

NCBI ID: G386685

KRTAP10-12: A Potential Drug Target and Biomarker

KRTAP10-12 (KRTAP18.12) is a protein that is expressed in various tissues of the body, including the brain, heart, lungs, and kidneys. It is a member of the Kallikrein-related peptidases (KLK) family 18.12, which is a group of serine proteases that are involved in the regulation of various cellular processes, including inflammation, cell signaling, and tissue repair.

KRTAP10-12 has been identified as a potential drug target due to its involvement in the regulation of cellular processes that are important for human health and disease. For example, KRTAP10-12 has been shown to play a role in the development and progression of various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

In addition to its potential as a drug target, KRTAP10-12 has also been shown to be a valuable biomarker for several diseases. For example, KRTAP10-12 has been used as a biomarker for cancer, as it has been shown to be overexpressed in various types of cancer. Additionally, KRTAP10-12 has been used as a biomarker for neurodegenerative diseases, as it has been shown to be affected in these conditions.

KRTAP10-12 is also a good candidate for a diagnostic biomarker for various diseases. Its expression has been shown to be affected in a variety of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. This makes KRTAP10-12 an attractive candidate for use as a diagnostic biomarker for these conditions.

In conclusion, KRTAP10-12 is a protein that has been shown to be involved in the regulation of various cellular processes that are important for human health and disease. Its potential as a drug target and biomarker make it an attractive candidate for further research. Further studies are needed to fully understand the role of KRTAP10-12 in these processes and its potential as a therapeutic agent.

Protein Name: Keratin Associated Protein 10-12

Functions: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins

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