KRTAP1-4: A Potential Drug Target and Biomarker (G728255)

Target Name: KRTAP1-4

NCBI ID: G728255

KRTAP1-4: A Potential Drug Target and Biomarker

Keratin associated protein 1-4 (KRTAP1-4) is a protein that is expressed in various tissues, including hair, skin, and nails. It is a member of the keratin gene family and is involved in the regulation of cell growth, differentiation, and survival. KRTAP1-4 has also been shown to play a role in the development and progression of various diseases, including cancer. As a result, KRTAP1-4 has potential as a drug target and biomarker.

The KRTAP1-4 gene was identified and isolated in 2004 by researchers at the University of California, San Diego. The gene is located on chromosome 18 and encodes a protein of 21 kDa. KRTAP1-4 is a member of the keratin family, which is a large gene family that includes proteins involved in the regulation of cell growth, differentiation, and structure. The kRTAP gene family is one of the largest gene families in the human genome, with over 20 known genes.

KRTAP1-4 is expressed in various tissues and is involved in the regulation of cell growth, differentiation, and survival.

Studies have shown that KRTAP1-4 plays a role in the regulation of cell growth and differentiation. In one study, researchers found that KRTAP1-4 was involved in the regulation of the growth and differentiation of human hair follicles. They found that KRTAP1-4 was involved in the production of new hair strands and in the growth of individual hairs.

KRTAP1-4 has also been shown to play a role in the regulation of cell survival. In another study, researchers found that KRTAP1-4 was involved in the regulation of cell survival and that its expression was associated with the survival of cancer cells.

In addition to its role in cell growth and survival, KRTAP1-4 has also been shown to play a role in the regulation of cell differentiation. In one study, researchers found that KRTAP1-4 was involved in the regulation of stem cell differentiation and that its expression was associated with the differentiation of stem cells into functional tissues.

KRTAP1-4 has potential as a drug target and biomarker due to its involvement in the regulation of cell growth, differentiation, and survival.

As a result of its involvement in these processes, KRTAP1-4 has potential as a drug target. Drugs that target KRTAP1-4 have the potential to treat a variety of conditions, including cancer, hair loss, and skin and nail disorders. For example, one drug that has been shown to target KRTAP1-4 is Q30, which is a small molecule that inhibits the activity of KRTAP1-4. Q30 has been shown to be effective in treating hair loss and has the potential to be used as a treatment for other conditions that are caused by the regulation of cell growth and differentiation.

In addition to its potential as a drug target, KRTAP1-4 also has potential as a biomarker. Its involvement in the regulation of cell growth, differentiation, and survival makes it a valuable tool for the study of these processes. For example, KRTAP1-4 has been shown to be involved in the regulation of the growth and differentiation of various tissues, including hair, skin, and nails. Its expression has also been shown to be associated with the development and progression of various diseases, including cancer. As a result, KRTAP1-4 has the potential to be used as a biomarker for a variety of conditions.

In conclusion, KRTAP1-4 is a protein that is involved in the regulation of cell growth, differentiation, and survival. Its potential as a drug target and biomarker makes it an attractive target for

Protein Name: Keratin Associated Protein 1-4

Functions: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins

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