Target Name: OR4L1
NCBI ID: G122742
Other Name(s): Olfactory receptor family 4 subfamily L member 1 | Olfactory receptor 4L1 | Olfactory receptor, family 4, subfamily L, member 2 pseudogene | olfactory receptor OR14-28 | olfactory receptor family 4 subfamily L member 1 | Olfactory receptor 4L2 | OR14-28 | Olfactory receptor OR14-28 | olfactory receptor 4L2 | OR4L1_HUMAN | olfactory receptor, family 4, subfamily L, member 2 pseudogene | OR4L2P

OR4L1 Receptor: A Potential Drug Target for Olfactory Processing and Cancer

Olfactory receptor family 4 subfamily L member 1 (OR4L1) is a G protein-coupled receptor that plays a crucial role in human olfaction, also known as smell. OR4L1 is a transmembrane protein that is expressed in the sensory neurons of the nose, including the Olfactory epithelium and olfactory hypothelium. Its main function is to sense odor and convert it into neural signals, which are then transmitted through the nervous system to the brain for olfactory processing.

The OR4L1 receptor is an important component of the olfactory system and is associated with olfactory processing in the brain. Research shows that when people smell an odor, the olfactory cortex area of 鈥嬧?媡he brain is stimulated, resulting in an olfactory experience. In addition, the OR4L1 receptor is also closely related to the cognitive and memory processes of smell.

Due to its important role in the olfactory system, the OR4L1 receptor is considered a potential drug target. Some researchers are exploring the use of antihistamines to agonize the OR4L1 receptor to treat various odor-related diseases, including odor allergies and cancer.

In addition, the OR4L1 receptor may serve as a potential biomarker to detect the progression of certain cancers. For example, some researchers are exploring the use of the OR4L1 receptor as a biomarker for colon cancer detection in nasal swabs. They believe that because OR4L1 receptors are highly expressed in the nasal cavity, nasal swab detection of OR4L1 receptor levels could serve as a reliable method to detect colon cancer progression.

The OR4L1 receptor has also been linked to the efficacy of certain drugs. For example, some studies show that antihistamines can reduce symptoms caused by odor allergies, such as nasal congestion and sneezing. This is because these drugs agonize the OR4L1 receptor, which reduces the inflammatory response caused by histamine in the nasal cavity.

In addition, the OR4L1 receptor is also closely related to odor memory and learning processes. Research shows that the OR4L1 receptor is associated with the hippocampus and amygdala regions of the brain, which are closely related to odor memory and learning processes. Therefore, the researchers believe that odor memory and learning processes can be improved by activating the OR4L1 receptor.

In conclusion, OR4L1 receptor plays an important role in the olfactory system. By agonizing the OR4L1 receptor, it could treat odor allergies and cancer and serve as a biomarker to detect the progression of certain cancers. In addition, the OR4L1 receptor is also closely related to drug efficacy and odor memory and learning processes. Therefore, the OR4L1 receptor is a potential drug target worthy of further research and exploration.

Protein Name: Olfactory Receptor Family 4 Subfamily L Member 1

Functions: Odorant receptor

More Common Targets

OR4M1 | OR4M2 | OR4M2-OT1 | OR4N2 | OR4N3P | OR4N4 | OR4N5 | OR4P4 | OR4Q3 | OR4S1 | OR4S2 | OR4T1P | OR4V1P | OR4X1 | OR4X2 | OR51A1P | OR51A2 | OR51A3P | OR51A4 | OR51A6P | OR51A7 | OR51B2 | OR51B4 | OR51B5 | OR51B6 | OR51C1P | OR51D1 | OR51E1 | OR51E2 | OR51F1 | OR51F2 | OR51G1 | OR51G2 | OR51H1 | OR51I1 | OR51I2 | OR51J1 | OR51L1 | OR51M1 | OR51Q1 | OR51S1 | OR51T1 | OR51V1 | OR52A1 | OR52A4P | OR52A5 | OR52B2 | OR52B4 | OR52B6 | OR52D1 | OR52E1 | OR52E2 | OR52E4 | OR52E5 | OR52E6 | OR52E8 | OR52H1 | OR52I1 | OR52I2 | OR52J3 | OR52K1 | OR52K2 | OR52K3P | OR52L1 | OR52M1 | OR52N1 | OR52N4 | OR52N5 | OR52R1 | OR52W1 | OR52Z1P | OR56A1 | OR56A3 | OR56A4 | OR56A5 | OR56B1 | OR56B4 | OR5A1 | OR5A2 | OR5AC1 | OR5AC2 | OR5AK2 | OR5AK4P | OR5AN1 | OR5AP2 | OR5AR1 | OR5AS1 | OR5AU1 | OR5B12 | OR5B17 | OR5B2 | OR5B21 | OR5B3 | OR5BA1P | OR5C1 | OR5D13 | OR5D14 | OR5D16 | OR5D17P | OR5D18