HMGB4: Protein with Multiple Functions in The Body (G127540)

Target Name: HMGB4

NCBI ID: G127540

HMGB4: Protein with Multiple Functions in The Body

HMGB4 (HMGB4_HUMAN), also known as protamine HMB4, is a protein that is expressed in various tissues of the human body, including the muscle, heart, liver, and kidney. It is a component of the myosin head complex, which is responsible for the mechanical force generated by muscle contractions.

HMGB4 is a unique protein that has been shown to have a variety of functions in various physiological processes in the body. One of the most interesting functions of HMGB4 is its role in muscle function and development.

Research has shown that HMGB4 plays a critical role in the regulation of muscle growth and maintenance. It has been shown to be involved in the regulation of muscle protein synthesis and degradation, as well as in the regulation of muscle cell size and function.

Another function of HMGB4 is its role in the regulation of inflammation. Studies have shown that HMGB4 is involved in the regulation of inflammation response and has been shown to have anti-inflammatory properties.

HMGB4 has also been shown to have a variety of potential drug targets. For example, it has been shown to be involved in the regulation of cellular signaling pathways, including the TGF-β pathway. This pathway is involved in the regulation of cell growth, differentiation, and inflammation, and is a potential target for a variety of therapeutic drugs.

In addition to its potential drug targets, HMGB4 is also a potential biomarker for a variety of diseases. For example, studies have shown that HMGB4 levels are often elevated in a variety of diseases, including cancer, cardiovascular disease, and neurological disorders.

Overall, HMGB4 is a protein that has a variety of functions in the body, including its role in muscle function and development, its involvement in the regulation of inflammation, and its potential as a drug target and biomarker. Further research is needed to fully understand the role of HMGB4 in these processes and to develop effective therapies based on its properties.

Protein Name: High Mobility Group Box 4

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