HMMR: A Potential Drug Target for Cellular Stress and Cancer (G3161)

Target Name: HMMR

NCBI ID: G3161

HMMR: A Potential Drug Target for Cellular Stress and Cancer

HMMR (CD168), a protein that belongs to the heat shock protein (HSP) family, is a key regulator of cellular stress responses and has been identified as a potential drug target in various diseases, including cancer.

HMMR is a 21-kDa protein that is expressed in a variety of tissues, including the brain, heart, liver, and muscle. It is involved in the regulation of protein folding and localization, as well as in the detoxification of oxidative stress.

Recent studies have suggested that HMMR plays a crucial role in the pathogenesis of several diseases, including cancer. For example, it has been shown to be overexpressed in various types of cancer, and to contribute to the development of cancer-induced neurodegeneration.

In addition to its potential role in cancer, HMMR has also been suggested as a potential drug target for treating a variety of other diseases. For example, it has been shown to be involved in the regulation of inflammation, and to play a role in the development of autoimmune diseases.

HMMR is also a good candidate for a potential drug target because of its unique structure and its ability to interact with a variety of different molecules. This makes it a promising target for small molecules, as well as for drugs that target other proteins.

In conclusion, HMMR is a protein that has the potential to be a drug target for a variety of diseases. Further research is needed to fully understand its role in the regulation of cellular stress responses and to develop effective treatments for diseases that are caused by its dysfunction.

Protein Name: Hyaluronan Mediated Motility Receptor

Functions: Receptor for hyaluronic acid (HA) (By similarity). Involved in cell motility (By similarity). When hyaluronan binds to HMMR, the phosphorylation of a number of proteins, including PTK2/FAK1 occurs. May also be involved in cellular transformation and metastasis formation, and in regulating extracellular-regulated kinase (ERK) activity. May act as a regulator of adipogenisis (By similarity)

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