ANKRD46: A Protein Implicated in Parkinson's, Addiction and Pain

Target Name: ANKRD46

NCBI ID: G157567

ANKRD46: A Protein Implicated in Parkinson's, Addiction and Pain

ANKRD46 (ANR46-HUMAN) is a protein that is expressed in various tissues of the human body, including the brain, heart, kidneys, and pancreas. It is a member of the ANKRD4 gene family, which encodes a protein that is involved in various cellular processes in the body. One of the unique features of ANKRD46 is its ability to interact with other proteins, including the neurotransmitter dopamine.

The ANKRD46 protein is known for its role in modulating the levels of dopamine in the brain, which is important for a wide range of physiological processes, including mood regulation, motivation, and pleasure. It is also involved in the development and maintenance of various neurological disorders, including Parkinson's disease and addiction.

Research has shown that ANKRD46 plays a crucial role in the development and progression of Parkinson's disease, a neurodegenerative disorder that affects millions of people worldwide. Studies have shown that ANKRD46 levels are decreased in the brains of individuals with Parkinson's disease, and that inhibiting ANKRD46 activity may be a potential therapeutic approach for this disorder.

In addition to its role in Parkinson's disease, ANKRD46 has also been shown to be involved in the development and maintenance of addiction. Studies have shown that ANKRD46 is involved in the release of dopamine from the brain, and that this process may be important for the development of addictive behaviors.

Furthermore, ANKRD46 has also been shown to play a role in the regulation of pain. Studies have shown that ANKRD46 is involved in the production of pain signals in response to tissue damage, and that this process may be important for the development of chronic pain.

In conclusion, ANKRD46 is a protein that is involved in various cellular processes in the human body. Its role in modulating the levels of dopamine, the development and progression of Parkinson's disease, addiction, and pain makes it an attractive drug target for future research. Further studies are needed to fully understand the role of ANKRD46 in these processes and to develop effective therapies for these disorders.

Protein Name: Ankyrin Repeat Domain 46

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