ANKRD24: A Potential Drug Target and Biomarker (G170961)

Target Name: ANKRD24

NCBI ID: G170961

ANKRD24: A Potential Drug Target and Biomarker

Ankyrin dehydrogenase 24 (ANKRD24) is a protein that is expressed in various tissues and cells in the human body. It is a key enzyme in the detoxification of xenobiotics, such as bacteria, viruses, and chemicals, which are harmful to the body. The ANKRD24 enzyme has been identified as a potential drug target and biomarker for various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

The ANKRD24 enzyme is a member of the Ankyrin dehydrogenase subfamily, which is a well-established family of NAD+-dependent enzymes that are involved in the detoxification of xenobiotics. The ANKRD24 enzyme is responsible for the detoxification of 24 different xenobiotics, including bacteria, viruses, and chemicals. This enzyme has a critical role in maintaining the homeostasis of the body and has been implicated in various diseases.

One of the key features of the ANKRD24 enzyme is its sensitivity to inhibitors. In fact, several studies have shown that inhibitors can significantly reduce the activity of the ANKRD24 enzyme. These inhibitors include various organic acids, such as acetic acid, furfuric acid, and propionic acid, which are naturally occurring compounds that are found in the body.

The potential drug targeting of ANKRD24 comes from the observation that inhibitors of the ANKRD24 enzyme have been shown to be effective in treating various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. For example, several studies have shown that inhibitors of the ANKRD24 enzyme can be effective in treating neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease.

In addition to its potential therapeutic applications, the ANKRD24 enzyme is also a potential biomarker for various diseases. The ANKRD24 enzyme is expressed in various tissues and cells in the body, including the brain, and has been shown to be involved in the detoxification of xenobiotics that are harmful to the body. Therefore, the ANKRD24 enzyme has the potential to serve as a biomarker for various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

In conclusion, ANKRD24 is a protein that is expressed in various tissues and cells in the human body and is involved in the detoxification of xenobiotics. Its potential therapeutic applications come from the observation that inhibitors of the ANKRD24 enzyme have been shown to be effective in treating various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. Furthermore, the ANKRD24 enzyme has the potential to serve as a biomarker for various diseases. Further research is needed to fully understand the role of ANKRD24 in the body and its potential as a drug target and biomarker.

Protein Name: Ankyrin Repeat Domain 24

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