CYP2T1P: A Drug Target / Disease Biomarker (G171523)

Target Name: CYP2T1P

NCBI ID: G171523

Other Name(s): Cytochrome P450 family 2 subfamily T member 1, pseudogene | cytochrome P450 family 2 subfamily T member 1, pseudogene | CYP2T2P

CYP2T1P: A Drug Target / Disease Biomarker

CYP2T1P is a gene that encodes for the CYP2T19 enzyme, which is a key player in the metabolism of many drugs, including some anti-inflammatory and opioid medications. The CYP2T1P gene has been identified as a potential drug target or biomarker for several reasons.

The CYP2T1P gene is located on chromosome 10p16 and has been implicated in various cardiovascular and psychiatric disorders, including cardiovascular disease, diabetes, and depression. Studies have shown that individuals with certain genetic variations in the CYP2T1P gene are at an increased risk of developing cardiovascular disease, which is a leading cause of death in humans.

Another potential drug target related to the CYP2T1P gene is the CYP2T9 gene, which encodes for the CYP2T9 enzyme, which is responsible for metabolizing many drugs, including some statins, beta blockers, and opioids. The CYP2T9 gene has been shown to have a role in the metabolism of many drugs, and individuals with certain genetic variations in the CYP2T9 gene may be more susceptible to side effects from these drugs.

The CYP2T1P gene has also been linked to the risk of developing addiction to opioids. Studies have shown that individuals with certain genetic variations in the CYP2T1P gene may be more likely to develop tolerance to opioids and may be at an increased risk of developing addiction. This suggests that the CYP2T1P gene may be a useful biomarker for monitoring individuals at risk for opioid addiction.

In addition to its potential as a drug target, the CYP2T1P gene has also been shown to have a role in the regulation of pain. Studies have shown that individuals with certain genetic variations in the CYP2T1P gene may be more resistant to pain medications and may require higher doses of these medications to achieve an adequate level of pain relief. This suggests that the CYP2T1P gene may be a useful biomarker for monitoring individuals with chronic pain.

Overall, the CYP2T1P gene has a significant impact on several aspects of human health, including cardiovascular disease, diabetes, and addiction. As such, it is a promising candidate for drug targeting and may be useful as a biomarker for monitoring individuals at risk for these conditions. Further research is needed to fully understand the role of the CYP2T1P gene in human health and to develop safe and effective therapies based on this understanding.

Protein Name: Cytochrome P450 Family 2 Subfamily T Member 1, Pseudogene

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