Target Name: ETV4
NCBI ID: G2118
Other Name(s): E1AF | Ets variant gene 4 (E1A enhancer-binding protein, E1AF) | ETS translocation variant 4 (isoform 1) | ets variant gene 4 (E1A enhancer-binding protein, E1AF) | ETV4 variant 2 | EWS protein/E1A enhancer binding protein chimera | Polyomavirus enhancer activator-3 | ETV4_HUMAN | ETS variant transcription factor 4, transcript variant 5 | PEAS3 | ETS variant transcription factor 4, transcript variant 1 | PEA3 | adenovirus E1A enhancer-binding protein | E1A-F | ETV4 variant 5 | ETS translocation variant 4 (isoform 3) | Polyomavirus enhancer activator 3 homolog | Protein PEA3 | Adenovirus E1A enhancer-binding protein | ETS variant 4 | ETS variant transcription factor 4 | ETS translocation variant 4 | Ets variant gene 4 (E1A enhancer binding protein, E1AF) | ETV4 variant 1 | polyomavirus enhancer activator 3 homolog | ETS variant transcription factor 4, transcript variant 2

ETV4: A Potential Drug Target and Biomarker for Various Diseases

ETV4 (E1AF), also known as E1-伪 interleukin-4 receptor, is a protein that is expressed in various tissues throughout the body. It is a member of the interleukin-4 receptor family, which is a protein that is involved in the regulation of immune and inflammatory responses.

ETV4 is a potential drug target, as it has been shown to play a role in the development and progression of various diseases. For example, studies have shown that high levels of ETV4 expression are associated with an increased risk of developing cardiovascular disease, and that blocking the activity of ETV4 may be a promising approach for treating this condition.

In addition to its potential as a drug target, ETV4 has also been shown to be a potential biomarker for various diseases. For example, studies have shown that ETV4 is expressed in the lungs, heart, and brain, and that it is involved in the regulation of immune responses and inflammation. This suggests that ETV4 may be a useful biomarker for diseases that affect these tissues, such as cancer, autoimmune disorders, and neurodegenerative diseases.

Overall, ETV4 is a protein that has the potential to be a drug target and a biomarker for various diseases. Further research is needed to fully understand its role and to develop safe and effective treatments.

Protein Name: ETS Variant Transcription Factor 4

Functions: Transcriptional activator (PubMed:19307308, PubMed:31552090). May play a role in keratinocyte differentiation (PubMed:31552090)

More Common Targets

ETV5 | ETV6 | ETV7 | Eukaryotic translation initiation factor 2-alpha kinase | Eukaryotic translation initiation factor 2B | Eukaryotic translation initiation factor 3 (eIF-3) complex | Eukaryotic Translation Initiation Factor 4A (eIF-4A) | Eukaryotic Translation Initiation Factor 4E Binding Protein | EVA1A | EVA1A-AS | EVA1B | EVA1C | EVC | EVC2 | EVI2A | EVI2B | EVI5 | EVI5L | EVL | EVPL | EVPLL | EVX1 | EVX1-AS | EVX2 | EWSAT1 | EWSR1 | EXD1 | EXD2 | EXD3 | EXO1 | EXO5 | EXOC1 | EXOC1L | EXOC2 | EXOC3 | EXOC3-AS1 | EXOC3L1 | EXOC3L2 | EXOC3L4 | EXOC4 | EXOC5 | EXOC5P1 | EXOC6 | EXOC6B | EXOC7 | EXOC8 | Exocyst complex | EXOG | EXOGP1 | Exon junction complex | EXOSC1 | EXOSC10 | EXOSC10-AS1 | EXOSC2 | EXOSC3 | EXOSC4 | EXOSC5 | EXOSC6 | EXOSC7 | EXOSC8 | EXOSC9 | Exosome Complex | EXPH5 | EXT1 | EXT2 | EXTL1 | EXTL2 | EXTL2P1 | EXTL3 | EXTL3-AS1 | EYA1 | EYA2 | EYA3 | EYA4 | EYS | EZH1 | EZH2 | EZHIP | EZR | F10 | F11 | F11-AS1 | F11R | F12 | F13A1 | F13B | F2 | F2R | F2RL1 | F2RL2 | F2RL3 | F3 | F5 | F7 | F8 | F8A1 | F8A2 | F8A3 | F9 | FA2H