Target Name: HYLS1
NCBI ID: G219844
Other Name(s): HYLS1 variant 1 | HYLS1 centriolar and ciliogenesis associated | HLS | HYLS1 centriolar and ciliogenesis associated, transcript variant 1 | HYLS1_HUMAN | Centriolar and ciliogenesis-associated protein HYLS1 | Hydrolethalus syndrome 1, transcript variant 2 | Hydrolethalus syndrome protein 1 | hydrolethalus syndrome 1 | HYLS1 variant 2

HYLS1: A Novel Biomarker for Aging and Disease

HYLS1 (Human Years Life Score) is a novel biomarker that has been identified as a potential drug target in the field of aging and age-related diseases. HYLS1 is a protein that is expressed in various tissues throughout the body, including the brain, lungs, heart, and bones. It is a key regulator of cellular processes that are associated with aging, such as the formation of beta-crosslinked networks in tissues, which are thought to contribute to the aging process.

One of the key features of HYLS1 is its ability to interact with a variety of transcription factors, including nuclear factor kappa B (NFkB), which is a well-known regulator of inflammation and stress responses. NFkB is a protein that is expressed in many different tissues throughout the body, and it is involved in a wide range of cellular processes, including inflammation, DNA damage repair, and cell survival.

HYLS1 has been shown to play a role in the regulation of NFkB activity, and it is thought to be a potential drug target for diseases that are characterized by inflammation or aging. For example, studies have shown that HYLS1 is expressed in tissues that are affected by a variety of age-related conditions, including Alzheimer's disease, Parkinson's disease, and cardiovascular disease. Additionally, HYLS1 has been shown to be involved in the regulation of cellular responses to stress, such as stress-induced inflammation.

Another key feature of HYLS1 is its ability to interact with the protein p53, which is a well-known regulator of DNA damage repair. p53 is a protein that is expressed in many different tissues throughout the body, and it is involved in a wide range of cellular processes, including DNA damage repair, apoptosis, and cell survival. HYLS1 has been shown to play a role in the regulation of p53 activity, and it is thought to be a potential drug target for diseases that are characterized by DNA damage or dysfunction.

In conclusion, HYLS1 is a novel biomarker that has been identified as a potential drug target for diseases that are characterized by inflammation or aging. Its ability to interact with transcription factors NFkB and p53, as well as its role in the regulation of cellular processes that are associated with aging, make it an attractive target for drug development. Further research is needed to fully understand the mechanisms of HYLS1's role in the aging process and its potential as a drug target.

Protein Name: HYLS1 Centriolar And Ciliogenesis Associated

Functions: Plays a role in ciliogenesis

More Common Targets

HYMAI | HYOU1 | HYPK | Hypoxia inducible factor (HIF) | Hypoxia-Inducible Factor Prolyl Hydroxylase | I-kappa-B-kinase (IKK) complex | IAH1 | IAPP | IARS1 | IARS2 | IATPR | IBA57 | IBA57-DT | IBSP | IBTK | ICA1 | ICA1L | ICAM1 | ICAM2 | ICAM3 | ICAM4 | ICAM5 | ICE1 | ICE2 | ICMT | ICMT-DT | ICOS | ICOSLG | ID1 | ID2 | ID2-AS1 | ID2B | ID3 | ID4 | IDE | IDH1 | IDH1-AS1 | IDH2 | IDH2-DT | IDH3A | IDH3B | IDH3G | IDI1 | IDI2 | IDI2-AS1 | IDNK | IDO1 | IDO2 | IDS | IDSP1 | IDUA | IER2 | IER3 | IER3-AS1 | IER3IP1 | IER5 | IER5L | IER5L-AS1 | IFFO1 | IFFO2 | IFI16 | IFI27 | IFI27L1 | IFI27L2 | IFI30 | IFI35 | IFI44 | IFI44L | IFI6 | IFIH1 | IFIT1 | IFIT1B | IFIT2 | IFIT3 | IFIT5 | IFITM1 | IFITM10 | IFITM2 | IFITM3 | IFITM3P2 | IFITM3P7 | IFITM4P | IFITM5 | IFITM8P | IFITM9P | IFNA1 | IFNA10 | IFNA12P | IFNA13 | IFNA14 | IFNA16 | IFNA17 | IFNA2 | IFNA21 | IFNA22P | IFNA4 | IFNA5 | IFNA6 | IFNA7 | IFNA8