IFI27L2: A Potential Drug Target for Inflammation and Autoimmune Diseases

Target Name: IFI27L2

NCBI ID: G83982

IFI27L2: A Potential Drug Target for Inflammation and Autoimmune Diseases

IFI27L2 (TLH29) is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. It is a member of the IFI27 family, which is known for its role in intracellular signaling. IFI27L2 has been shown to play a role in the regulation of inflammation and immune responses, and is potential drug target or biomarker.

The IFI27 family consists of four proteins: IFI27L1, IFI27L2, IFI27L3, and IFI27L4. All of these proteins share a conserved catalytic core and a similar structure, with the exception of IFI27L4, which has a more complex architecture. IFI27L2 is a 29 kDa protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. It is highly conserved, with a calculated pI of 11.95.

IFI27L2 is involved in a wide range of physiological processes in the body, including inflammation and immune responses. One of its most well-studied functions is its role in the regulation of inflammation. IFI27L2 has been shown to play a negative role in the regulation of inflammatory responses, by preventing the recruitment of immune cells to the site of inflammation. This protein has also been shown to play a role in the regulation of neuroinflammation, by modulating the activity of immune cells in the central nervous system.

IFI27L2 is also involved in the regulation of cell signaling pathways that are important for many cellular processes, including cell growth, apoptosis, and angiogenesis. It has been shown to play a role in the regulation of cell proliferation, by preventing the inhibition of the cell cycle by negative signaling pathways. IFI27L2 has also been shown to play a role in the regulation of cell apoptosis, by promoting the production of pro-apoptotic proteins.

IFI27L2 is a potential drug target or biomarker due to its involvement in a wide range of physiological processes that are important for human health. Its role in the regulation of inflammation and immune responses makes it an attractive target for the development of therapeutic agents that can treat a variety of inflammatory and autoimmune diseases. Additionally, its role in the regulation of cell signaling pathways makes it an attractive target for the development of therapeutic agents that can modulate cellular processes that are important for many cellular processes, including cancer progression. Further research is needed to fully understand the role of IFI27L2 in human physiology and to develop effective therapeutic agents.

Protein Name: Interferon Alpha Inducible Protein 27 Like 2

Functions: Plays a role in the apoptotic process and has a pro-apoptotic activity

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