GABRG1: A Potential Drug Target and Biomarker for GABA Receptor-Mediated Signaling
GABRG1: A Potential Drug Target and Biomarker for GABA Receptor-Mediated Signaling
GABA (gamma-aminobutyric acid) is a neurotransmitter that plays a crucial role in the regulation of neural circuits and is involved in a wide range of physiological processes, including sensory perception, motor control, and mood regulation. The GABA receptor, GABRG1, is a GABA receptor that has been identified as a potential drug target and biomarker for various neurological and psychiatric disorders.
The GABA receptor is a transmembrane protein that consists of an extracellular portion and an intracellular portion. The extracellular portion of the GABA receptor is composed of a N-terminus that is involved in cell-extracellular interactions and a C-terminus that is involved in protein-protein interactions. The intracellular portion of the GABA receptor contains a pre-synaptic terminal that is involved in the interaction with GABA and a post-synaptic terminal that is involved in the interaction with other signaling molecules.
GABRG1 is a GABA receptor that is expressed in many different tissues and cells, including brain, spinal cord, and peripheral tissues. It is involved in the regulation of a wide range of physiological processes, including neuronal excitability, synaptic plasticity, and neurotransmitter signaling. GABRG1 has been shown to play a role in the regulation of pain, anxiety, and depression, as well as in the modulation of sleep and wakefulness.
GABRG1 has also been shown to be involved in the regulation of neurotransmitter signaling, including the regulation of glutamate and GABA neurotransmitters. GABRG1 has been shown to play a negative role in the regulation of glutamate neurotransmission, which is involved in the modulation of synaptic plasticity and learning. GABRG1 has also been shown to play a positive role in the regulation of GABA neurotransmission, which is involved in the regulation of pain perception and anxiety.
In addition to its role in neurotransmission, GABRG1 is also involved in the regulation of a wide range of cellular processes, including cell survival, cell migration, and cell adhesion. GABRG1 has been shown to play a role in the regulation of cell survival and cell migration, as well as in the regulation of cell adhesion.
GABRG1 has also been shown to be involved in the regulation of inflammation, including the regulation of the immune response and the regulation of inflammatory pain. GABRG1 has been shown to play a role in the regulation of the immune response, including the regulation of T-cell function and the regulation of inflammation.
GABRG1 has also been shown to be involved in the regulation of energy metabolism, including the regulation of glucose metabolism and the regulation of lipid metabolism. GABRG1 has been shown to play a role in the regulation of glucose metabolism, including the regulation of insulin sensitivity and the regulation of glucose uptake and storage. GABRG1 has also been shown to play a role in the regulation of lipid metabolism, including the regulation of lipid uptake and storage.
In conclusion, GABRG1 is a GABA receptor that is involved in a wide range of physiological processes. Its role in the regulation of neurotransmission, cellular processes, inflammation, and energy metabolism makes it a potential drug target and biomarker for a wide range of neurological and psychiatric disorders. Further research is needed to fully understand the role of GABRG1 in these processes and to develop effective treatments for disorders that are characterized by the disruption of GABA receptor function.
Protein Name: Gamma-aminobutyric Acid Type A Receptor Subunit Gamma1
Functions: GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel
More Common Targets
GABRG2 | GABRG3 | GABRG3-AS1 | GABRP | GABRQ | GABRR1 | GABRR2 | GABRR3 | GACAT1 | GACAT2 | GACAT3 | GAD1 | GAD2 | GADD45A | GADD45B | GADD45G | GADD45GIP1 | GADL1 | GAGE1 | GAGE10 | GAGE12B | GAGE12C | GAGE12D | GAGE12F | GAGE12G | GAGE12H | GAGE12J | GAGE2A | GAGE2B | GAGE2C | GAGE2D | GAGE4 | GAGE5 | GAGE6 | GAGE7 | GAGE8 | GAK | GAL | GAL3ST1 | GAL3ST2 | GAL3ST3 | GAL3ST4 | Galanin receptor | GALC | GALE | GALK1 | GALK2 | GALM | GALNS | GALNT1 | GALNT10 | GALNT11 | GALNT12 | GALNT13 | GALNT13-AS1 | GALNT14 | GALNT15 | GALNT16 | GALNT17 | GALNT18 | GALNT2 | GALNT3 | GALNT4 | GALNT5 | GALNT6 | GALNT7 | GALNT7-DT | GALNT8 | GALNT9 | GALNT9-AS1 | GALNTL5 | GALNTL6 | GALP | GALR1 | GALR2 | GALR3 | GALT | Gamma Crystallin | Gamma-Aminobutyric acid type B receptor | Gamma-aminobutyric-acid A receptor, Rho | gamma-delta T Cell Receptor (TCR) Complex | Gamma-glutamyl transferase | gamma-Secretase | Gamma-tubulin complex | GAMT | GAN | GANAB | GANC | Gap junction Connexin ( | Gap Junction Protein | GAP43 | GAPDH | GAPDHP1 | GAPDHP14 | GAPDHP21 | GAPDHP38 | GAPDHP42 | GAPDHP56 | GAPDHP62 | GAPDHP65