SNORA64: A Small Nucleolar RNA with Potential as a Drug Target or Biomarker

Target Name: SNORA64

NCBI ID: G26784

Other Name(s): small nucleolar RNA, H/ACA box 64 | RNU64 | U64 | Small nucleolar RNA, H/ACA box 64

SNORA64: A Small Nucleolar RNA with Potential as a Drug Target or Biomarker

Small nucleolar RNA (snRNA) is a non-coding RNA molecule that plays a crucial role in various cellular processes, including DNA replication, gene expression, and stress response. One of the well-known snRNAs is H/ACA box 64 (SNORA64), which is a 22-nt RNA molecule located within the H/ACA box region on chromosome 9q34.

SNORA64 is expressed in various cell types and is involved in the regulation of gene expression. Its functions include regulating microRNA (miRNA) levels, influencing chromatin structure and accessibility, and modulating the expression of target genes.

Recent studies have identified potential drug targets and biomarkers associated with SNORA64. In this article, we will explore the potential of SNORA64 as a drug target and biomarker, highlighting recent research in the field and discussing the implications of these findings.

Potential Drug Targets

SNORA64 has been identified as a potential drug target due to its involvement in various cellular processes that are crucial for human health. One of the potential drug targets associated with SNORA64 is the regulation of cell apoptosis.

Studies have shown that SNORA64 is involved in the regulation of cell apoptosis, which is a natural process that helps remove damaged or dysfunctional cells from the body. During apoptosis, SNORA64 helps to ensure that the cell undergoes proper degradation and removal, which is necessary for maintaining tissue homeostasis and overall cellular health.

Additionally, SNORA64 has been shown to be involved in the regulation of cell cycle progression. It has been shown to play a role in the regulation of microtubule dynamics and the assembly/disassembly of microtubules, which are critical for cell division and growth.

Potential Biomarkers

SNORA64 has also been identified as a potential biomarker for various diseases, including cancer. Its involvement in the regulation of cellular processes makes it a promising biomarker for diseases that involve disruptions in normal cellular function.

Studies have shown that SNORA64 is expressed abnormally in various types of cancer, including breast, ovarian, and colorectal cancer. Additionally, altered SNORA64 levels have been associated with cancer progression and poor prognosis.

In addition to its potential as a biomarker, SNORA64 has also been shown to be involved in the regulation of cellular signaling pathways. It has been shown to play a role in the regulation of the PI3K/Akt signaling pathway, which is involved in various cellular processes, including cell survival, angiogenesis, and inflammation.

Conclusion

In conclusion, SNORA64 is a small nucleolar RNA that plays a crucial role in various cellular processes. Its functions include regulating cell apoptosis, cell cycle progression, and cellular signaling pathways. Recent studies have identified potential drug targets and biomarkers associated with SNORA64, which have implications for the development of new therapies and treatments for various diseases.

While further research is needed to fully understand the functions of SNORA64 and its potential as a drug target and biomarker, its identification and characterization as a promising target for future research is significant. As research continues to advance, the potential of SNORA64 as a drug target and biomarker will be further validated, and its role in the regulation of cellular processes will continue to be explored.

Protein Name: Small Nucleolar RNA, H/ACA Box 64

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