Target Name: GLB1
NCBI ID: G2720
Other Name(s): Hydrolact | Lactase | Acid beta-galactosidase | beta-D-lactosidase | Lactozym | Trilactase | Galactosidase beta 1 | galactosidase beta 1 | EBP | Maxilact | elastin binding protein | Beta-galactosidase isoform c precursor (isoform c) | Elastin receptor 1, 67kDa | beta-D-Galactoside galactohydrolase | S 2107 | Beta-galactosidase isoform a preproprotein (isoform a) | elastin receptor 1, 67kDa | Oryzatym | GLB1 variant 4 | uncharacterized LOC105377022 | Beta-galactosidase | beta-Galactosidase preprotein | Elastin receptor 1 | beta-D-galactanase | GLB1 variant 3 | Bgal | ELNR1 | GLB1 variant 1 | MPS4B | BGAL_HUMAN | Beta-galactosidase isoform d precursor (isoform d) | Sumiklat | beta-Lactosidase | lactase | acid beta-galactosidase

GLB1: A Protein with Both Pro-Inflammation and Anti-Inflammation Properties

GLB1 (Hydrolact), also known as GLB1-1, is a protein that is expressed in various tissues of the body, including the brain, pancreas, and skin. It is a member of the GLB1 family, which consists of several similar proteins that are involved in various cellular processes. One of the unique features of GLB1 is its ability to induce a range of cellular responses, including the production of antibodies and the activation of signaling pathways that are involved in inflammation, cell proliferation, and apoptosis.

GLB1 has also been shown to play a role in several diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. Its role in these diseases has led to a growing interest in using GLB1 as a potential drug target or biomarker.

One of the main reasons for the interest in GLB1 is its potential as a drug target is its ability to induce both pro-inflammatory and anti-inflammatory responses in cells. This is important because many diseases are characterized by an imbalance of these two types of responses. For example, in cancer, inflammation can promote the growth and survival of cancer cells, while in neurodegenerative diseases, inflammation can contribute to the destruction of neural tissue.

GLB1 has been shown to play a role in the production of antibodies, which are proteins that are designed to recognize and neutralize foreign substances in the body. When GLB1 is activated, it can induce the production of antibodies that are specific to GLB1 itself. This is important because GLB1 has been shown to be involved in the development of autoimmune disorders, which are characterized by the production of antibodies against self-antigens.

In addition to its role in the production of antibodies, GLB1 has also been shown to play a role in the regulation of signaling pathways that are involved in inflammation and cell proliferation. For example, GLB1 has been shown to be involved in the production of pro-inflammatory cytokines, such as TNF-alpha and IL-1尾, as well as the regulation of anti-inflammatory factors, such as ITGGF-1.

GLB1 has also been shown to play a role in the regulation of cell apoptosis, which is the process by which cells die when they have reached a certain level of dysfunction or when they are no longer needed. In cancer, GLB1 has been shown to promote the apoptosis of normal cells, which can help to prevent the development of cancer. In neurodegenerative diseases, GLB1 has been shown to contribute to the dysfunction and progression of neurodegeneration.

Despite its potential as a drug target or biomarker, GLB1 is still a relatively unstudied protein. There is currently limited research on the effects of GLB1, and much of the research that has been done on GLB1 is focused on its role in autoimmune diseases and cancer.

In conclusion, GLB1 is a protein that is expressed in various tissues of the body and is involved in a range of cellular processes. Its ability to induce both pro-inflammatory and anti-inflammatory responses in cells makes it an attractive potential drug target or biomarker for a variety of diseases. Further research is needed to fully understand the role of GLB1 in these diseases and to develop effective treatments.

Protein Name: Galactosidase Beta 1

Functions: Cleaves beta-linked terminal galactosyl residues from gangliosides, glycoproteins, and glycosaminoglycans

More Common Targets

GLB1L | GLB1L2 | GLB1L3 | GLC1C | GLCCI1 | GLCCI1-DT | GLCE | GLDC | GLDN | GLE1 | GLG1 | GLI1 | GLI2 | GLI3 | GLI4 | GLIDR | GLIPR1 | GLIPR1L1 | GLIPR1L2 | GLIPR2 | GLIS1 | GLIS2 | GLIS3 | GLIS3-AS1 | GLMN | GLMP | GLO1 | GLOD4 | GLOD5 | GLP1R | GLP2R | GLRA1 | GLRA2 | GLRA3 | GLRA4 | GLRB | GLRX | GLRX2 | GLRX3 | GLRX3P2 | GLRX5 | GLS | GLS2 | GLT1D1 | GLT6D1 | GLT8D1 | GLT8D2 | GLTP | GLTPD2 | Glucagon-like peptide receptor (GLP-R) | Glucosidase | GLUD1 | GLUD1P2 | GLUD1P3 | GLUD2 | GLUL | GLULP2 | GLULP4 | Glutamate receptor | Glutamate Receptor Ionotropic | Glutamate Receptor Ionotropic AMPA Receptor | Glutamate Transporter | Glutaminase | Glutathione peroxidase | Glutathione S-Transferase (GST) | GLYAT | GLYATL1 | GLYATL1B | GLYATL2 | GLYATL3 | GLYCAM1 | Glycine receptor | Glycogen phosphorylase | Glycogen synthase | Glycogen synthase kinase 3 (GSK-3) | Glycoprotein hormone | Glycoprotein Hormone Receptor | GLYCTK | Glycylpeptide N-tetradecanoyltransferase | Glypican | GLYR1 | GM-CSF Receptor (GM-CSF-R) | GM1 ganglioside | GM2A | GM2AP1 | GM2AP2 | GMCL1 | GMCL2 | GMDS | GMDS-DT | GMEB1 | GMEB2 | GMFB | GMFG | GMIP | GML | GMNC | GMNN | GMPPA | GMPPB