RP7A: A Potential Drug Target for Neurodegenerative Diseases (G27341)

Target Name: RRP7A

NCBI ID: G27341

RP7A: A Potential Drug Target for Neurodegenerative Diseases

RP7A (BK126B4.3) is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. It is a member of the superfamily of RNA-protein binding proteins (SPP), which are a group of proteins that interact with RNA molecules. RP7A is also known as BK126B4.3 and has been identified as a potential drug target in the field of neurodegenerative diseases.

RP7A is expressed in the brain and is involved in the regulation of various cellular processes, including cell survival, migration, and synaptic plasticity. It is also involved in the regulation of ion channels, which are important for the flow of electrical signals in the brain.

RP7A has been shown to play a role in the development and progression of several neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease, and Huntington's disease. It is thought to interact with several protein molecules, including tau, a protein that is involved in the development of Alzheimer's disease, and neurotrophin, a protein that is involved in the survival of neurons.

RP7A is also shown to interact with several small molecules, including drugs that are currently being used to treat neurodegenerative diseases. These drugs include deep-sea exploration and neurotrophin.

RP7A is a protein that is expressed in various tissues of the body and is involved in the regulation of various cellular processes. It is also involved in the regulation of ion channels and has been shown to play a role in the development and progression of several neurodegenerative diseases. It is a potential drug target and may be useful in the treatment of these diseases.

Protein Name: Ribosomal RNA Processing 7 Homolog A

Functions: Nucleolar protein that is involved in ribosomal RNA (rRNA) processing (PubMed:33199730). Also plays a role in primary cilia resorption, and cell cycle progression in neurogenesis and neocortex development (PubMed:33199730). Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (PubMed:34516797)

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