Target Name: RSPH3
NCBI ID: G83861
Other Name(s): Radial spoke head 3 homolog (chlamydomonas, RSPH3) | dJ111C20.1 | Radial spoke head protein 3 homolog isoform 1 | Radial spoke head-like protein 2 | RSP3 | Radial spoke head 3, transcript variant 1 | radial spoke head 3 homolog | RSPH3_HUMAN | CILD32 | Radial spoke head protein 3 homolog | A-kinase anchor protein RSPH3 | Radial spokehead-like 2 | radial spoke head 3 | radial spoke head-like protein 2 | radial spoke 3 homolog | Radial spoke head 3 homolog | Radial spoke protein 3 | RSHL2 | RSPH3 variant 1

Radial Spoke Head 3: Potential Drug Target and Biomarker

Radial spoke head 3 (RSPH3) is a protein that is found in the cytosol of the green algae Chlamydomonas. RSPH3 is a member of the Radial Spoke Head (RSPH) family which are characterized by the presence of a radial spoke-like structure in the cytosol of the cell. The RSPH3 protein has been identified as a potential drug target and a biomarker for various diseases.

The RSPH3 protein is involved in various cellular processes such as photosynthesis, pigmentation, and cell signaling. It is a key regulator of the Chlamydomonas genome and is involved in the expression of many different genes.

One of the key functions of RSPH3 is its role in the regulation of photosynthesis. RSPH3 is involved in the formation of the chlorophyll a pigment, which is essential for photosynthesis. RSPH3 is also involved in the regulation of the photosynthetic apparatus, including the electron transport chain and the ATP synthase.

In addition to its role in photosynthesis, RSPH3 is also involved in the regulation of cell signaling. It has been shown to play a role in the regulation of cell growth, differentiation, and stress response. RSPH3 has also been shown to interact with various signaling pathways, including the TOR signaling pathway and the AP-1 signaling pathway.

RSPH3 is also a potential drug target for several diseases. Its involvement in photosynthesis and cell signaling make it a potential target for diseases that are related to these processes, such as cancer, neurodegenerative diseases, and diseases that involve inflammation. In addition, its role in cell growth and differentiation make it a potential target for diseases that involve uncontrolled cell growth, such as cancer.

Furthermore, RSPH3 has also been shown to be a potential biomarker for several diseases. Its involvement in the regulation of photosynthesis and cell signaling make it a potential indicator of overall health and well-being. In addition, its involvement in the regulation of cell growth and differentiation make it a potential indicator of the effectiveness of certain treatments.

In conclusion, RSPH3 is a protein that is involved in various cellular processes that are essential for life. Its role in the regulation of photosynthesis, cell signaling, and cell growth makes it a potential drug target and biomarker for several diseases. Further research is needed to fully understand its role in these processes and to develop effective treatments.

Protein Name: Radial Spoke Head 3

Functions: Functions as part of axonemal radial spoke complexes that play an important part in the motility of sperm and cilia (By similarity). Functions as a protein kinase A-anchoring protein that scaffolds the cAMP-dependent protein kinase holoenzyme. May serve as a point of convergence for MAPK and PKA signaling in cilia (PubMed:19684019)

More Common Targets

RSPH4A | RSPH6A | RSPH9 | RSPO1 | RSPO2 | RSPO3 | RSPO4 | RSPRY1 | RSRC1 | RSRC2 | RSRP1 | RSU1 | RSU1P2 | RTBDN | RTCA | RTCB | RTEL1 | RTEL1-TNFRSF6B | RTF1 | RTF2 | RTKN | RTKN2 | RTL1 | RTL10 | RTL3 | RTL4 | RTL5 | RTL6 | RTL8A | RTL8B | RTL8C | RTL9 | RTN1 | RTN2 | RTN3 | RTN4 | RTN4IP1 | RTN4R | RTN4RL1 | RTN4RL2 | RTP1 | RTP2 | RTP3 | RTP4 | RTP5 | RTRAF | RTTN | RUBCN | RUBCNL | RUFY1 | RUFY2 | RUFY3 | RUFY4 | RUNDC1 | RUNDC3A | RUNDC3A-AS1 | RUNDC3B | RUNX1 | RUNX1-IT1 | RUNX1T1 | RUNX2 | RUNX2-AS1 | RUNX3 | RUNX3-AS1 | RUSC1 | RUSC1-AS1 | RUSC2 | RUSF1 | RUVBL1 | RUVBL1-AS1 | RUVBL2 | RWDD1 | RWDD2A | RWDD2B | RWDD3 | RWDD3-DT | RWDD4 | RXFP1 | RXFP2 | RXFP3 | RXFP4 | RXRA | RXRB | RXRG | RXYLT1 | Ryanodine receptor | RYBP | RYK | RYR1 | RYR2 | RYR3 | RZZ complex | S100 Calcium Binding Protein | S100A1 | S100A10 | S100A11 | S100A11P1 | S100A12 | S100A13 | S100A14