Target Name: RWDD1
NCBI ID: G51389
Other Name(s): RWDD1 variant 1 | RWD domain-containing protein 1 (isoform a) | PTD013 | RWDD1_HUMAN | RWD domain containing 1 | CGI-24 | RWD domain-containing protein 1 | DFRP2 | DRG family-regulatory protein 2 | RWD domain containing 1, transcript variant 1

RWDD1: A Potential Drug Target and Biomarker for Neurological Disorders

RWDD1 (RWDD1 variant 1) is a protein that is expressed in the brain and is involved in the regulation of cell death. It has been shown to play a role in various neurological disorders, including Alzheimer's disease, Parkinson's disease, and Huntington's disease.

RWDD1 is a scaffold protein that is involved in the formation of the endoplasmic reticulum, which is the system responsible for the degradation of damaged or unnecessary proteins. It is part of a family of proteins called the transmembrane protein superfamily, which includes proteins that are involved in the formation of tight junctions, which are a type of cell-cell barrier.

RWDD1 is expressed in the brain and is involved in the regulation of cell death, which is a critical process in the development and progression of neurological disorders. It has been shown to play a role in the development of neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease, and Huntington's disease.

One of the most promising aspects of RWDD1 is its potential as a drug target. Researchers have identified several potential drug targets for RWDD1, including those that are involved in the formation of neurodegenerate structures, such as amyloid plaques, which are a hallmark of Alzheimer's disease.

Another potential drug target for RWDD1 is its role in the regulation of cell death. Studies have shown that RWDD1 is involved in the formation of apoptotic cells, which are cells that are programmed to die as part of a normal cell death process. This may provide a potential therapeutic target for diseases that are characterized by the formation of these cells, such as neurodegenerative diseases.

In addition to its potential as a drug target, RWDD1 has also been shown to be a potential biomarker for the diagnosis and progression of neurological disorders. Studies have shown that RWDD1 is expressed in the brains of individuals with neurodegenerative diseases, and that its levels are associated with the severity of these conditions. This may provide a potential diagnostic or predictive tool for these diseases.

Overall, RWDD1 is a protein that has the potential to be a drug target and a biomarker for the diagnosis and progression of neurological disorders. Further research is needed to fully understand its role and to develop effective treatments for these conditions.

Protein Name: RWD Domain Containing 1

Functions: Protects DRG2 from proteolytic degradation

More Common Targets

RWDD2A | RWDD2B | RWDD3 | RWDD3-DT | RWDD4 | RXFP1 | RXFP2 | RXFP3 | RXFP4 | RXRA | RXRB | RXRG | RXYLT1 | Ryanodine receptor | RYBP | RYK | RYR1 | RYR2 | RYR3 | RZZ complex | S100 Calcium Binding Protein | S100A1 | S100A10 | S100A11 | S100A11P1 | S100A12 | S100A13 | S100A14 | S100A16 | S100A2 | S100A3 | S100A4 | S100A5 | S100A6 | S100A7 | S100A7A | S100A7L2 | S100A7P1 | S100A8 | S100A9 | S100B | S100G | S100P | S100PBP | S100Z | S1PR1 | S1PR1-DT | S1PR2 | S1PR3 | S1PR4 | S1PR5 | SAA1 | SAA2 | SAA2-SAA4 | SAA3P | SAA4 | SAAL1 | SAC3D1 | SACM1L | SACS | SACS-AS1 | SAE1 | SAFB | SAFB2 | SAG | SAGA complex | SAGE1 | SALL1 | SALL2 | SALL3 | SALL4 | SALL4P7 | SALRNA2 | SAMD1 | SAMD10 | SAMD11 | SAMD12 | SAMD12-AS1 | SAMD13 | SAMD14 | SAMD15 | SAMD3 | SAMD4A | SAMD4A-AS1 | SAMD4B | SAMD5 | SAMD7 | SAMD8 | SAMD9 | SAMD9L | SAMHD1 | SAMM50 | SAMMSON | SAMSN1 | SAMSN1-AS1 | SANBR | SAP130 | SAP18 | SAP30 | SAP30-DT