S100Z: A Drug Target / Disease Biomarker (G170591)

Target Name: S100Z

NCBI ID: G170591

S100Z: A Drug Target / Disease Biomarker

S100Z is a protein that is expressed in various tissues throughout the body, including the brain, heart, and muscles. It is a member of the S100 family of proteins, which are known as the brain-associated protein family. This family of proteins is involved in a wide range of cellular processes, including cell signaling, neurotransmitter release, and neuroprotection. S100Z is unique among the S100 proteins in that it is expressed in the brain, and it is thought to play a key role in the function of this organ.

S100Z is involved in a number of different processes in the brain, including the regulation of neurotransmitter release, the establishment of the blood-brain barrier, and the modulation of pain perception. It is thought to work by interacting with specific molecules in the brain, including neurotransmitters, ion channels, and signaling proteins.

One of the key functions of S100Z is its role in modulating neurotransmitter release. This is an important process that is involved in the transmission of signals from the brain to other parts of the body. S100Z is involved in the regulation of neurotransmitter release by interacting with the neurotransmitter receptor, a protein that is found in the brain. This interaction allows S100Z to regulate the release of neurotransmitters, such as dopamine and serotonin, which are involved in a wide range of brain functions.

S100Z is also involved in the regulation of the blood-brain barrier, which is a specialized barrier that separates the brain from the bloodstream. This barrier is designed to protect the brain from harmful substances that could cause damage, but it also makes it difficult for certain substances to reach the brain. S100Z is thought to play a key role in the regulation of the blood-brain barrier, as it is known to interact with the protein known as tight junction protein (TJP). This protein helps to maintain the integrity of the blood-brain barrier by regulating the movement of cells into and out of the brain.

In addition to its role in modulating neurotransmitter release, S100Z is also thought to be involved in the regulation of pain perception. This is an important process that is involved in the perception of pain and the regulation of pain sensitivity. S100Z is thought to play a key role in the regulation of pain perception by interacting with the protein known as TrkA, which is involved in the transmission of pain signals from the body to the brain. This interaction allows S100Z to regulate the expression of genes involved in pain perception, which may help to reduce the intensity of pain signals.

S100Z is also a potential drug target, as it is thought to be involved in a wide range of cellular processes that are involved in the development and progression of a variety of diseases. For example, S100Z has been shown to be involved in the regulation of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease. It is also thought to be involved in the regulation of cancer cell growth and the development of certain types of cancer.

Overall, S100Z is a protein that is involved in a wide range of cellular processes in the body. It is expressed in the brain and is thought to play a key role in the regulation of neurotransmitter release, the establishment of the blood-brain barrier, and the modulation of pain perception. As a result, S100Z is a potential drug target that could be used to treat a wide range of diseases.

Protein Name: S100 Calcium Binding Protein Z

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