SAFB2: A Promising Drug Target and Biomarker (G9667)

Target Name: SAFB2

NCBI ID: G9667

Other Name(s): SAF-B2 | SAFB2_HUMAN | Scaffold attachment factor B2 | KIAA0138 | scaffold attachment factor B2

SAFB2: A Promising Drug Target and Biomarker

SAFB2 (Safety-BREAKpoint 2) is a drug target and potential biomarker that is being studied for its potential utility in treating various diseases, including cancer. SAFB2 is a protein that is expressed in various tissues throughout the body, including the brain, and has been shown to play a role in a variety of physiological processes.

One of the most promising aspects of SAFB2 is its potential as a drug target. SAFB2 has been shown to be involved in a variety of signaling pathways that are important for cancer development and progression. For example, SAFB2 has been shown to be involved in the regulation of cell growth, apoptosis (programmed cell death), and angiogenesis (the formation of new blood vessels).

SAFB2 has also been shown to be involved in the regulation of neurotransmitter signaling, which is important for brain function and development. SAFB2 has been shown to play a role in the regulation of dopamine and serotonin signaling, which are important for mood, emotion, and memory.

In addition to its potential role in drug development, SAFB2 also has potential as a biomarker for various diseases. For example, SAFB2 has been shown to be elevated in the brains of individuals with Alzheimer's disease, which is a degenerative brain disorder that is characterized by progressive memory loss and other cognitive impairments.

SAFB2 has also been shown to be elevated in the brains of individuals with Parkinson's disease, which is a neurodegenerative disorder that is characterized by motor symptoms such as tremors and stiffness.

In addition to its potential role in drug development and biomarker research, SAFB2 is also of interest to researchers because of its unique structure and biology. SAFB2 is a protein that is expressed in a variety of tissues throughout the body, including the brain, and has a unique mechanism of regulation that allows it to be targeted by small molecules.

This unique mechanism of regulation makes SAFB2 an attractive candidate for drug development as a treatment for a variety of diseases. By targeting SAFB2 with small molecules, researchers can potentially improve the safety and effectiveness of drug treatments.

Overall, SAFB2 is a drug target and biomarker that has the potential to improve the safety and effectiveness of drug treatments. Further research is needed to fully understand its biology and develop safe and effective treatments.

Protein Name: Scaffold Attachment Factor B2

Functions: Binds to scaffold/matrix attachment region (S/MAR) DNA. Can function as an estrogen receptor corepressor and can also inhibit cell proliferation

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