SAMD4A-AS1: A Potential Drug Target and Biomarker (G729451)

Target Name: SAMD4A-AS1

NCBI ID: G729451

Other Name(s): SAMD4A antisense RNA 1, transcript variant X1 | SAMD4A antisense RNA 1

SAMD4A-AS1: A Potential Drug Target and Biomarker

SAMD4A-AS1 is a non-coding RNA molecule that has been identified as an antisense RNA 1 in the SAMD4A gene family. It is a unique RNA molecule that is found in various cell types of the human body, including blood cells, immune cells, and epithelial cells. SAMD4A-AS1 has been shown to play a critical role in regulating cell proliferation and has been linked to various diseases, including cancer. As a result, SAMD4A-AS1 has gained significant interest as a potential drug target and biomarker.

SAMD4A-AS1 functions as an antisense RNA, which means it interacts with mRNAs to inhibit their translation into proteins. This process is known as post-transcriptional modification (PTM) and has been shown to play a crucial role in the regulation of gene expression. SAMD4A-AS1 has been shown to interact with several target mRNAs, including MAX, a transcription factor that is known to play a role in cancer progression.

SAMD4A-AS1 has also been shown to interact with the protein encoded by the gene IPF1, which is known to contribute to the development of various diseases, including cancer. The interaction between SAMD4A-AS1 and IPF1 has led to the idea that SAMD4A-AS1 may be a useful biomarker for the diagnosis and treatment of cancer.

In addition to its potential role as a drug target, SAMD4A-AS1 has also been shown to have potential as a diagnostic biomarker. The expression of SAMD4A-AS1 has been shown to be downregulated in various types of cancer, including breast, ovarian, and prostate cancer. This suggests that SAMD4A-AS1 may be a useful biomarker for the diagnosis and assessment of cancer risk.

Furthermore, the levels of SAMD4A-AS1 have been shown to be elevated in various diseases, including cardiovascular disease and autoimmune disorders. This suggests that SAMD4A-AS1 may be a potential diagnostic biomarker for these diseases as well.

In conclusion, SAMD4A-AS1 is a non-coding RNA molecule that has been identified as an antisense RNA 1 in the SAMD4A gene family. It has been shown to play a critical role in regulating cell proliferation and has been linked to various diseases, including cancer. As a result, SAMD4A-AS1 has gained significant interest as a potential drug target and biomarker. Further research is needed to fully understand the role of SAMD4A-AS1 in disease progression and its potential as a diagnostic biomarker.

Protein Name: SAMD4A Antisense RNA 1

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