S100P: A Protein with Multiple Functions and Potential as A Drug

Target Name: S100P

NCBI ID: G6286

S100P: A Protein with Multiple Functions and Potential as A Drug

S100P, also known as 100 calcium-binding protein P, is a protein that is expressed in various tissues throughout the body. It is a member of the S100 family of proteins, which are known for their ability to interact with calcium ions. S100P is unique among these proteins because of its ability to form a covalent complex with calcium ions, which allows it to regulate various cellular processes.

One of the key functions of S100P is its role in cell signaling. S100P is involved in a variety of signaling pathways, including the regulation of cell growth, differentiation, and inflammation. It is also involved in the regulation of muscle contraction and in the development of certain diseases, such as cancer.

Another important function of S100P is its role in tissue repair and regeneration. S100P is involved in the regulation of cell proliferation and has been shown to play a role in the repair and regeneration of damaged tissue. This makes it an attractive potential drug target for researchers , as diseases such as cancer and neurodegenerative disorders can result from the loss of tissue repair and regeneration capabilities.

In addition to its role in cell signaling and tissue repair, S100P is also involved in the regulation of immune response. It is a known regulator of the T-cell receptor, which is responsible for cell recognition and response to foreign substances in the body. S100P is also involved in the regulation of inflammation, which is critical for protecting the body against harmful substances and pathogens.

S100P is also involved in the regulation of protein synthesis and has been shown to play a role in the regulation of protein synthesis in the cell. This makes it an interesting potential drug target, as diseases such as cancer and genetic disorders can result from disruptions in protein synthesis.

In conclusion, S100P is a unique and important protein that is involved in a variety of cellular processes. Its ability to form a covalent complex with calcium ions and its involvement in cell signaling, tissue repair, and regeneration make it an attractive potential drug target for researchers. Additionally, S100P's role in the regulation of immune response and protein synthesis also adds to its potential as a drug. Further studies are needed to fully understand the role of S100P in these processes and to determine its potential as a drug.

Protein Name: S100 Calcium Binding Protein P

Functions: May function as calcium sensor and contribute to cellular calcium signaling. In a calcium-dependent manner, functions by interacting with other proteins, such as EZR and PPP5C, and indirectly plays a role in physiological processes like the formation of microvilli in epithelial cells. May stimulate cell proliferation in an autocrine manner via activation of the receptor for activated glycation end products (RAGE)

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