OR11-260: A GPCR Targeted for Olfactory, Pain and Inflammation
OR11-260: A GPCR Targeted for Olfactory, Pain and Inflammation
Olfactory receptor OR11-260 is a G protein-coupled receptor (GPCR) that is expressed in the olfactory system of the human nose. It is one of the many GPCRs that are known to play a role in smell perception, and is thought to be involved in the detection of a wide range of odors.
Recent studies have suggested that OR11-260 may be a potential drug target for several reasons. First, GPCRs are known to be involved in a variety of physiological processes, including sensory perception, neurotransmission, and inflammation. As such, targeting GPCRs with small molecules that can modulate their activity may be a useful way to study their function and identify new treatments for a variety of diseases.
Second, OR11-260 is known to be involved in the regulation of pain perception, which is a key aspect of neuropathic pain. GPCRs are often involved in the transmission of pain signals from the body to the brain, and targeting them with drugs that can modulate their activity may be a promising approach to treating pain.
Third, OR11-260 has been shown to be involved in the regulation of inflammation, which is a key aspect of many diseases including autoimmune and inflammatory disorders. GPCRs are often involved in the regulation of inflammation, and targeting them with drugs that can modulate their activity may be a promising approach to treating these diseases.
Finally, OR11-260 is a good candidate for a drug target because of its unique structure and subcellular localization. GPCRs can be found in various cell types throughout the body, including neurons, endothelial cells, and immune cells. However, their localization to specific cell types can vary, and OR11-260 is localized to the olfactory system. This may make it an attractive target for small molecules that can modulate its activity.
In conclusion, OR11-260 is a GPCR that is involved in the regulation of olfactory perception, pain perception, and inflammation. Its unique structure and subcellular localization make it an attractive target for small molecules that can modulate its activity. Further research is needed to fully understand the role of OR11-260 in the olfactory system and its potential as a drug target.
Protein Name: Olfactory Receptor Family 4 Subfamily C Member 13
Functions: Odorant receptor
More Common Targets
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