KRT18P55: A Potential Drug Target and Biomarker (G284085)

KRT18P55: A Potential Drug Target and Biomarker

Keratin 18 (K18) pseudogene 55 (KRT18P55) is a gene that encodes a portion of the Keratin protein, which is a key component of hair, nails, and skin. Mutations in the K18 gene have been linked to a variety of human diseases, including alopecia areata, a progressive hair loss condition, and scalp psoriasis. In addition, KRT18P55 has also been shown to be involved in the development of skin tags and actinic dermatitis, which are common skin conditions.

Recent studies have identified KRT18P55 as a potential drug target and biomarker for a variety of skin and hair conditions. One of the reasons for its potential as a drug target is its involvement in the regulation of cell growth and differentiation. KRT18P55 has been shown to play a role in the regulation of stem cell proliferation and the differentiation of stem cells into functional epidermal cells, which are the cells responsible for the formation of hair and nails.

In addition, KRT18P55 has also been shown to be involved in the regulation of cell death and the detoxification of environmental toxins. Studies have shown that KRT18P55 promotes the programmed cell death (apoptosis) that occurs when cells are no longer able to repair their DNA damage, which can lead to the development of cancer. Furthermore, KRT18P55 has also been shown to play a role in the detoxification of environmental toxins, such as the herbicide 2,4-Dichlorophenoxyacetic acid (2,4-D), which has been linked to the development of skin tags and actinic dermatitis.

Another potential mechanism by which KRT18P55 may be involved in the development of skin and hair conditions is its role in the regulation of the immune system. Studies have shown that KRT18P55 is involved in the regulation of immune cell function and has been shown to play a role in the development of autoimmune diseases, such as alopecia areata and psoriasis.

In addition, KRT18P55 has also been shown to be involved in the regulation of cell signaling pathways, including the TGF-β pathway. This pathway is involved in the regulation of cell growth, differentiation, and the development of cancer. Studies have shown that KRT18P55 is involved in the regulation of TGF-β signaling and has been shown to play a role in the development of cancer.

Overall, KRT18P55 is a gene that has been shown to be involved in a variety of cellular processes that are important for the development and maintenance of hair, nails, and skin. Its potential as a drug target and biomarker makes it an attractive target for future research and development. Further studies are needed to fully understand the role of KRT18P55 in the development of skin and hair conditions and to determine its potential as a drug.

Protein Name: Keratin 18 Pseudogene 55

More Common Targets

KRT18P59 | KRT18P6 | KRT18P62 | KRT19 | KRT19P2 | KRT19P3 | KRT2 | KRT20 | KRT222 | KRT23 | KRT24 | KRT25 | KRT26 | KRT27 | KRT28 | KRT3 | KRT31 | KRT32 | KRT33A | KRT33B | KRT34 | KRT35 | KRT36 | KRT37 | KRT38 | KRT39 | KRT4 | KRT40 | KRT42P | KRT5 | KRT6A | KRT6B | KRT6C | KRT7 | KRT7-AS | KRT71 | KRT72 | KRT73 | KRT73-AS1 | KRT74 | KRT75 | KRT76 | KRT77 | KRT78 | KRT79 | KRT8 | KRT80 | KRT81 | KRT82 | KRT83 | KRT84 | KRT85 | KRT86 | KRT87P | KRT89P | KRT8P10 | KRT8P11 | KRT8P12 | KRT8P14 | KRT8P16 | KRT8P17 | KRT8P18 | KRT8P22 | KRT8P23 | KRT8P25 | KRT8P26 | KRT8P29 | KRT8P3 | KRT8P33 | KRT8P36 | KRT8P37 | KRT8P39 | KRT8P41 | KRT8P44 | KRT8P45 | KRT8P46 | KRT8P47 | KRT8P48 | KRT8P49 | KRT8P5 | KRT8P7 | KRT8P8 | KRT8P9 | KRT9 | KRT90P | KRTAP1-1 | KRTAP1-3 | KRTAP1-4 | KRTAP1-5 | KRTAP10-1 | KRTAP10-10 | KRTAP10-11 | KRTAP10-12 | KRTAP10-2 | KRTAP10-3 | KRTAP10-4 | KRTAP10-5 | KRTAP10-6 | KRTAP10-7 | KRTAP10-8