TRAJ58 Regulates T Cell Response and Immune Functions (G28697)

Target Name: TRAJ58

NCBI ID: G28697

Other Name(s): T cell receptor alpha joining 58 (non-functional)

TRAJ58 Regulates T Cell Response and Immune Functions

T cell receptor alpha-joining 58 (TRAJ58), also known as non-functional T cell receptor alpha-joining 58, is a protein that plays a critical role in the regulation of T cell responses. Trajectin 58 is a non-functional T cell receptor alpha-joining protein which can interact with the protein PD-L1. This interaction between the two proteins is crucial in regulating the regulation of T cell responses, including the regulation of cell proliferation and differentiation.

TRAJ58 is a protein that is expressed in various tissues, including the spleen, lymph nodes, and Peyer's patches. It is a 120-kDa protein that is composed of two heavy chains and two light chains. The heavy chains contain four variable regions, including a single constant region and three variable regions. The variable regions contain the amino acids that are responsible for the interaction between TRAJ58 and PD-L1.

The function of TRAJ58 is to form the alpha-chain of the T cell receptor. The alpha-chain is the portion of the T cell receptor that interacts with the PD-L1 protein. The interaction between TRAJ58 and PD-L1 allows for the regulation of T cell responses, including the regulation of cell proliferation and differentiation.

TRAJ58 is regulated by several factors, including cytokines, chemokines, and intracellular signaling pathways. One of the well-known regulations of TRAJ58 is the interaction with PD-L1. PD-L1 is a protein that is expressed in various tissues, including the spleen, lymph nodes, and Peyer's patches. It is a 160-kDa protein that is composed of two heavy chains and two light chains. The heavy chains contain four variable regions, including a single constant region and three variable regions. The variable regions contain the amino acids that are responsible for the interaction between PD-L1 and TRAJ58.

The interaction between TRAJ58 and PD-L1 is critical in regulating the regulation of T cell responses. TRAJ58 can interact with PD-L1 through its variable regions, allowing for the regulation of T cell responses. One of the well-known functions of TRAJ58 is its role in the regulation of cell proliferation and differentiation. TRAJ58 can interact with PD-L1 and regulate the activity of the transcription factor PDX-1, which is responsible for the regulation of cell proliferation and differentiation.

Another function of TRAJ58 is its role in the regulation of immune responses. TRAJ58 can interact with PD-L1 and regulate the activity of the transcription factor NF-kappa-B, which is responsible for the regulation of immune responses. TRAJ58 can also interact with the protein PD-1 and regulate the activity of the T cell receptor, allowing for the regulation of T cell responses.

TRAJ58 is also regulated by several signaling pathways, including the PI3K/Akt signaling pathway. This signaling pathway is responsible for the regulation of cell proliferation and differentiation, and TRAJ58 is regulated by this pathway through its interaction with PD-L1.

In conclusion, T cell receptor alpha-joining 58 (TRAJ58) is a non-functional T cell receptor alpha-joining protein that plays a critical role in the regulation of T cell responses. The interaction between TRAJ58 and PD-L1 is crucial in regulating the regulation of T cell responses, including the regulation of cell proliferation and differentiation, and the regulation of immune responses. Therefore, TRAJ58 is a potential drug target and a biomarker for the treatment of various diseases, including cancer, autoimmune diseases, and neurodegenerative diseases.

Protein Name: T Cell Receptor Alpha Joining 58 (non-functional)

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