TRAPPC5: A Protein Targeted for Cancer and Neurodegenerative Diseases

Target Name: TRAPPC5

NCBI ID: G126003

TRAPPC5: A Protein Targeted for Cancer and Neurodegenerative Diseases

Trafficking Protein Particle Complex Subunit 5 (TRAPPC5) is a protein that is expressed in various tissues and cells throughout the body. It is a part of a complex that is involved in the transport of proteins to the endoplasmic reticulum (ER), where they can be processed and degraded. This protein has been identified as a potential drug target and may also serve as a biomarker for various diseases.

The TRAPPC5 protein is composed of 118 amino acid residues and has a calculated molecular weight of 13.9 kDa. It is expressed in a variety of tissues, including the brain, heart, liver, and muscle. It is also found in the endoplasmic reticulum and is involved in the transport of proteins to this organ.

One of the unique features of TRAPPC5 is its role in the trafficking of proteins to the ER. The ER is a protein-rich organ that is involved in the processing and degrading of proteins. It is thought to play a crucial role in the development and progression of many diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

TRAPPC5 is part of a complex that is involved in the trafficking of proteins to the ER. This complex is composed of several subunits, including TRAPPC5, TRAPPC6, and TRAPPC7. These subunits are involved in the recruitment of proteins to the ER via its extracellular domain.

Studies have shown that TRAPPC5 plays a crucial role in the trafficking of proteins to the ER. In one experiment, researchers found that overexpression of TRAPPC5 caused a significant reduction in the amount of protein available in the ER, suggesting that it plays an important role in this process.

In addition to its role in protein trafficking, TRAPPC5 has also been identified as a potential drug target. Several studies have shown that TRAPPC5 is involved in the regulation of cellular processes that are important in the development of cancer.

One of the potential mechanisms by which TRAPPC5 may contribute to cancer development is its role in the regulation of the angiogenesis that occurs during the development of cancer. Angiogenesis is the process by which new blood vessels are formed, and it is thought to play a crucial role in the development of cancer.

Research has shown that TRAPPC5 is involved in the regulation of angiogenesis by the projection pathway. This pathway involves the migration of cells along the blood vessels and is thought to play a crucial role in the development of cancer.

Another potential mechanism by which TRAPPC5 may contribute to cancer development is its role in the regulation of the immune response. The immune response is a crucial part of the body's defense against cancer, and it is thought to play a crucial role in the regulation of cancer development.

Research has shown that TRAPPC5 is involved in the regulation of the immune response by the T cell receptor. This receptor is involved in the regulation of the immune response and is thought to play a crucial role in the development of cancer.

In conclusion, TRAPPC5 is a protein that is involved in the transport of proteins to the endoplasmic reticulum and has been identified as a potential drug target and biomarker for various diseases. Further research is needed to fully understand the role of TRAPPC5 in these processes and to develop effective treatments for these diseases.

Protein Name: Trafficking Protein Particle Complex Subunit 5

Functions: May play a role in vesicular transport from endoplasmic reticulum to Golgi

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