TRAT1: Key Regulator of T Cell Recognition and Activation (G50852)

Target Name: TRAT1

NCBI ID: G50852

TRAT1: Key Regulator of T Cell Recognition and Activation

TRAT1, also known as T cell receptor interacting molecule, is a protein that plays a crucial role in the immune system. It is a key regulator of the T cell receptor (TCR), which is a critical protein that helps T cells recognize and respond to foreign substances in the body. TRAT1 is a protein that interacts with the TCR, and it is essential for the proper functioning of T cells.

TRAT1 is a protein that is expressed in many different tissues throughout the body, including the brain, the lungs, the heart, and the gastrointestinal tract. It is also highly expressed in the T cells, which are a type of white blood cell that play a critical role in the immune system. TRAT1 is primarily localized to the cytoplasm of T cells, where it interacts with the TCR.

One of the key functions of TRAT1 is to regulate the activity of the TCR. The TCR is a protein that is composed of an alpha chain and a beta chain. The alpha chain is the part of the TCR that interacts with TRAT1, while the beta chain is the part of the TCR that interacts with other proteins. TRAT1 helps regulate the activity of the TCR by interacting with the alpha chain.

TRAT1 also helps regulate the activation and proliferation of T cells. When a T cell is activated, TRAT1 helps it transition from a state of dormancy to an active state. This allows the T cell to begin responding to foreign substances in the body. TRAT1 also helps regulate the proliferation of T cells by controlling the production of new T cells.

In addition to its role in regulating T cell activity, TRAT1 is also a potential drug target. Many studies have suggested that TRAT1 may be a useful target for cancer treatment, particularly in cases where T cells are over-expressed or where the TCR is not functioning properly. TRAT1 has also been shown to be involved in a variety of other biological processes, including cell signaling, migration, and invasion.

Overall, TRAT1 is a protein that plays a critical role in the immune system. Its interaction with the TCR is essential for the proper functioning of T cells, and it may be a useful target for cancer treatment. Further research is needed to fully understand the role of TRAT1 in the immune system and its potential as a drug target.

Protein Name: T Cell Receptor Associated Transmembrane Adaptor 1

Functions: Stabilizes the TCR (T-cell antigen receptor)/CD3 complex at the surface of T-cells

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