Target Name: TRAPPC2L
NCBI ID: G51693
Other Name(s): HSPC176 | hematopoietic stem/progenitor cells 176 | TRAPPC2L variant 2 | Hematopoietic stem/progenitor cells 176 | Trafficking protein particle complex subunit 2-like protein | Trafficking protein particle complex subunit 2L, transcript variant 2 | MGC111156 | FLJ44827 | Trafficking protein particle complex subunit 2-like protein (isoform 2) | trafficking protein particle complex 2 like | PERRB | TPC2L_HUMAN | trafficking protein particle complex subunit 2L

TRAPPC2L: A Protein Involved in Cell Signaling and Cell Survival

TRAPPC2L (HSPC176) is a protein that is expressed in various tissues throughout the body, including the brain, heart, and kidneys. It is a member of the TRAPPC family of proteins, which are involved in the regulation of protein synthesis and post-translational modification. HSPC176 is unique among TRAPPC2L family members because it is a type of transmembrane protein, meaning it spans the membrane of the cell and functions as an extracellular protein.

One of the key functions of TRAPPC2L is its role in cell signaling. It is involved in the regulation of several intracellular signaling pathways, including the TGF-β pathway, the PI3K/Akt pathway, and the NF-kappa-B pathway. These pathways are involved in a wide range of cellular processes, including cell growth, differentiation, angiogenesis, and inflammation.

TRAPPC2L is also involved in the regulation of protein synthesis and post-translational modification. It has been shown to play a role in the regulation of protein synthesis by interacting with the protein factors TOR and S6. These factors are involved in the regulation of cell growth and metabolism, and TRAPPC2L is thought to contribute to this regulation by interacting with them and regulating their activity.

Another function of TRAPPC2L is its role in cell signaling and protein synthesis is the regulation of cell survival. Studies have shown that TRAPPC2L is involved in the regulation of cell survival and that its activity can be modulated by a variety of factors, including exercise, starvation , and chemotherapy.

TRAPPC2L is also involved in the regulation of inflammation. It has been shown to play a role in the regulation of inflammation and that its activity can be modulated by factors such as inflammation, stress, and chemotactic factors.

TRAPPC2L is also a potential drug target. Studies have shown that inhibition of TRAPPC2L can lead to a variety of therapeutic effects, including the inhibition of cancer cell growth, the regulation of inflammation, and the modulation of cellular signaling pathways.

In conclusion, TRAPPC2L is a protein that is involved in several important cellular processes, including cell signaling, protein synthesis, cell survival, and inflammation. Its unique transmembrane properties and its involvement in multiple cellular processes make it an attractive target for drug development. Further research is needed to fully understand the role of TRAPPC2L in cellular processes and its potential as a drug target.

Protein Name: Trafficking Protein Particle Complex Subunit 2L

Functions: Plays a role in vesicular transport from endoplasmic reticulum to Golgi

More Common Targets

TRAPPC3 | TRAPPC3L | TRAPPC4 | TRAPPC5 | TRAPPC6A | TRAPPC6B | TRAPPC8 | TRAPPC9 | TRARG1 | TRAT1 | TRAV1-2 | TRAV10 | TRAV11 | TRAV12-1 | TRAV12-2 | TRAV13-2 | TRAV14DV4 | TRAV19 | TRAV2 | TRAV20 | TRAV21 | TRAV22 | TRAV24 | TRAV25 | TRAV26-1 | TRAV26-2 | TRAV27 | TRAV3 | TRAV34 | TRAV38-2DV8 | TRAV39 | TRAV4 | TRAV41 | TRAV8-1 | TRAV8-2 | TRAV8-3 | TRAV8-4 | TRAV8-6 | TRAV9-1 | TRBC1 | TRBC2 | TRBD1 | TRBD2 | TRBJ1-1 | TRBJ1-2 | TRBJ1-3 | TRBJ1-4 | TRBJ1-5 | TRBJ1-6 | TRBJ2-1 | TRBJ2-2 | TRBJ2-2P | TRBJ2-3 | TRBJ2-4 | TRBJ2-5 | TRBJ2-6 | TRBJ2-7 | TRBV10-1 | TRBV10-2 | TRBV10-3 | TRBV11-1 | TRBV11-2 | TRBV11-3 | TRBV12-3 | TRBV12-4 | TRBV12-5 | TRBV13 | TRBV14 | TRBV15 | TRBV16 | TRBV17 | TRBV18 | TRBV19 | TRBV2 | TRBV20-1 | TRBV21-1 | TRBV21OR9-2 | TRBV22-1 | TRBV23-1 | TRBV24-1 | TRBV25-1 | TRBV27 | TRBV28 | TRBV29-1 | TRBV3-1 | TRBV30 | TRBV4-1 | TRBV4-2 | TRBV4-3 | TRBV5-1 | TRBV5-2 | TRBV5-3 | TRBV5-4 | TRBV5-5 | TRBV5-6 | TRBV5-7 | TRBV5-8 | TRBV6-1 | TRBV6-2 | TRBV6-3