Target Name: ZNF181
NCBI ID: G339318
Other Name(s): ZN181_HUMAN | zinc finger protein 181 | HHZ181 | ZNF181 variant 1 | Zinc finger protein 181 | Zinc finger protein 181, transcript variant 1 | Zinc finger protein 181 (isoform 1)

ZNF181: A Potential Drug Target for Neurological and Psychiatric Disorders

ZNF181 (ZN181_HUMAN), a protein encoded by the Zinc Finger N-Code (ZNF) gene, is a key regulator of neural development and function. ZNF181 has been implicated in a wide range of physiological processes, including neuronal plasticity, neurogenesis, and stress response. As a result, ZNF181 has emerged as a promising drug target for the treatment of various neurological and psychiatric disorders.

The ZNF gene is a member of the ZNF family, which includes several similar genes that share a conserved zinc-finger domain. These genes are involved in the regulation of neural development and function, including the development and maintenance of neuronal stem cells, the generation of diverse neurotransmitter systems, and the regulation of stress response. The ZNF gene is expressed in many tissues and cell types, including brain, spinal cord, and peripheral tissues.

ZNF181 is a 21-kDa protein that is predominantly expressed in the brain. It is involved in the regulation of neuronal excitability and synaptic plasticity, which are critical for the development and maintenance of neural circuitry. ZNF181 has been shown to play a role in the regulation of neurotransmitter release and synaptic plasticity, as well as in the modulation of ion channels and other signaling pathways that are involved in neural activity.

In addition to its role in neural development and function, ZNF181 has also been implicated in the regulation of various stress responses, including stress-induced neurodegeneration and neuroinflammation. This is thought to be due to the fact that ZNF181 is involved in the regulation of cellular stress responses, as well as in the regulation of pro-inflammatory responses that are involved in the pathophysiology of stress-induced neurological disorders.

Given the wide range of physiological processes that are involved in ZNF181, it is not surprising that it has been identified as a potential drug target for a wide range of neurological and psychiatric disorders. For example, ZNF181 has been shown to be involved in the regulation of neurotransmitter release and synaptic plasticity, which are critical for the development and maintenance of neural circuitry. As a result, ZNF181 has been implicated in the pathophysiology of a wide range of disorders, including depression, anxiety, and neurodegenerative diseases.

In addition to its role in the regulation of neural activity, ZNF181 has also been shown to play a role in the regulation of cellular stress responses. This is thought to be due to the fact that ZNF181 is involved in the regulation of pro-inflammatory responses that are involved in the pathophysiology of stress-induced neurological disorders. For example, ZNF181 has been shown to be involved in the regulation of the expression of genes involved in the production of pro-inflammatory cytokines, such as TNF-伪 and IL-1尾.

Given the wide range of potential drug targets that have been identified for ZNF181, there is a need for further research to fully understand its role in the regulation of neural development and function. This will be an important step in the development of new treatments for a wide range of neurological and psychiatric disorders.

Protein Name: Zinc Finger Protein 181

Functions: May be involved in transcriptional regulation

More Common Targets

ZNF182 | ZNF184 | ZNF185 | ZNF189 | ZNF19 | ZNF195 | ZNF197 | ZNF2 | ZNF20 | ZNF200 | ZNF202 | ZNF204P | ZNF205 | ZNF205-AS1 | ZNF207 | ZNF208 | ZNF209P | ZNF211 | ZNF212 | ZNF213 | ZNF213-AS1 | ZNF214 | ZNF215 | ZNF217 | ZNF219 | ZNF22 | ZNF22-AS1 | ZNF221 | ZNF222 | ZNF223 | ZNF224 | ZNF225 | ZNF225-AS1 | ZNF226 | ZNF227 | ZNF229 | ZNF23 | ZNF230 | ZNF232 | ZNF232-AS1 | ZNF233 | ZNF234 | ZNF235 | ZNF236 | ZNF236-DT | ZNF239 | ZNF24 | ZNF248 | ZNF25 | ZNF250 | ZNF251 | ZNF252P | ZNF252P-AS1 | ZNF253 | ZNF254 | ZNF256 | ZNF257 | ZNF26 | ZNF260 | ZNF263 | ZNF264 | ZNF266 | ZNF267 | ZNF268 | ZNF271P | ZNF273 | ZNF274 | ZNF275 | ZNF276 | ZNF277 | ZNF28 | ZNF280A | ZNF280B | ZNF280C | ZNF280D | ZNF281 | ZNF282 | ZNF283 | ZNF284 | ZNF285 | ZNF285CP | ZNF286A | ZNF286B | ZNF287 | ZNF292 | ZNF295-AS1 | ZNF296 | ZNF3 | ZNF30 | ZNF300 | ZNF300P1 | ZNF302 | ZNF304 | ZNF311 | ZNF316 | ZNF317 | ZNF318 | ZNF319 | ZNF32 | ZNF32-AS1