ILA: Key Regulator of T Cell Development and Function (G3604)

Target Name: TNFRSF9

NCBI ID: G3604

ILA: Key Regulator of T Cell Development and Function

TNFRSF9 (T cell antigen ILA), also known as interleukin-3 (IL-3), is a protein that is expressed in various tissues of the body, including the immune system. It is a key regulator of T cell development and function, and is involved in the regulation of cell proliferation, differentiation, and survival.

ILA is a type of cytokine that is expressed by T cells, which are a crucial part of the immune system. T cells are responsible for recognizing and responding to foreign substances in the body, and are a key part of the immune response. ILA plays a key role in this process, as it helps to stimulate the development and activation of T cells.

One of the key functions of ILA is its role in T cell development. ILA is a critical signaling molecule that helps to regulate the development of T cells from stem cells. When stem cells differentiate into T cells, ILA plays a key role in this process, as it helps to stimulate the growth and proliferation of the stem cells.

ILA is also involved in the regulation of T cell function. When T cells are activated, ILA is released and helps to stimulate the production of other cytokines, such as interferon and transforming growth factor (TGF-β). These cytokines help to regulate the growth, survival, and differentiation of T cells.

ILA is also involved in the regulation of cell death. When T cells are no longer needed, ILA is released and helps to stimulate the production ofprogrammed cell death (PD-1). PD-1 is a cytokine that helps to induce cell death, and is a key part of the immune response.

TNFRSF9 is also a potential drug target. The ability of ILA to regulate T cell development and function makes it an attractive target for drug development. There are currently several drugs that are being developed to treat various types of cancer, including T cell malignancies. These drugs work by targeting ILA and inhibiting its activity.

In addition to its potential as a drug target, ILA is also an attractive biomarker for cancer. The ability of ILA to regulate T cell development and function makes it an important marker for cancer. Researchers are currently using ILA as a biomarker to diagnose and monitor various types of cancer.

In conclusion, TNFRSF9 (T cell antigen ILA) is a protein that is expressed in various tissues of the body and plays a key role in the regulation of T cell development and function. It is a potential drug target and a valuable biomarker for cancer. Further research is needed to fully understand the role of ILA in the immune system and its potential as a therapeutic agent.

Protein Name: TNF Receptor Superfamily Member 9

Functions: Receptor for TNFSF9/4-1BBL. Possibly active during T cell activation

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