VN1R10P: A Potential Drug Target for GPCRs (G387316)
VN1R10P: A Potential Drug Target for GPCRs
VN1R10P (b24o18.2) is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. Its full name is VN1 receptor subfamily 1 member 10 protein, and it is a member of the superfamily of G protein-coupled receptors (GPCRs). GPCRs are a family of transmembrane proteins that play a critical role in cellular signaling, and they are involved in many different processes in the body, including sensory perception, neurotransmission, and hormone signaling.
One of the unique features of VN1R10P is its structure. It is a 194-amino acid protein with a calculated molecular mass of 21.9 kDa. It consists of a single transmembrane domain and a single cytoplasmic tail. The transmembrane domain is made up of a single There are many connected 伪-helices, while the cytoplasmic tail contains a short asymmetric 伪-helix.
VN1R10P is a potent modulator of several GPCRs, including the GPCR known as SMOR. SMOR is a GPCR that is involved in the regulation of cell proliferation and survival, and it is a potential drug target for various diseases, including cancer.
One of the reasons why VN1R10P is considered a drug target is its unique structure. The multiple transmembrane regions and the presence of multiple intracellular loops make it a difficult target for small molecules. However, recent studies have shown that small molecules can still interact with VN1R10P and modulate its activity.
Another reason why VN1R10P is a drug target is its location in the body. The brain is a difficult target for drugs because of its ethical and safety concerns. However, because VN1R10P is expressed in the brain, it is a promising target for drugs that can modulate its activity and potentially treat various neurological and psychiatric disorders.
In addition to its potential as a drug target, VN1R10P is also a biomarker for several diseases. Its expression has been shown to be elevated in several diseases, including cancer, neurodegenerative diseases, and psychiatric disorders. This makes it a potential diagnostic or monitoring tool for these diseases.
Overall, VN1R10P is a unique protein that has the potential to be a drug target for various diseases. Its structure and location in the body make it a difficult target, but its role as a biomarker for several diseases makes it a promising target for future research . Further studies are needed to fully understand its potential and to develop safe and effective drugs that can modulate its activity.
Protein Name: Vomeronasal 1 Receptor 10 Pseudogene
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